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Table 2 Total number of variants affecting protein in extracellular and intracellular TLRs

From: Non-synonymous genetic variation in exonic regions of canine Toll-like receptors

Canine gene

ENSEMBL protein ID

Protein length (aa)

AA change ratio a

Extracellular TLRs

   

TLR1

ENSCAFP00000032660

790

1/113

TLR2

ENSCAFP00000012269

785

1/196

TLR4

ENSCAFP00000031395

833

1/69

TLR5

ENSCAFP00000016726

1422

1/53

TLR6

ENSCAFP00000023836

797

1/199

TLR10

ENSCAFP00000023840

807

1/269

Intracellular TLRs

   

TLR3

ENSCAFP00000011004

905

1/905

TLR7

ENSCAFP00000017193

1121

1/374

TLR8

ENSCAFP00000031505

1038

1/260

TLR9

ENSCAFP00000030804

1032

1/129

  1. Variants from CanFam 3.1 have been added to variants identified by massive sequencing in this table. aAA change ratio: aminoacid changes caused by nsSNPs or frameshift mutations divided by the length of the protein in aminoacids.