Fig. 5

Proportion of genome- and exome-wide coverage by merging reads from different libraries. Left panel: The proportion of the genome with zero coverage (gray color) or with 1–3x coverage (orange color) when one library was compared with merging the reads from two, three or four sequencing libraries. With one library sequenced with two Ion Proton PI chips 3.43 % of the genome was not covered (0 coverage) and 13.72 % had coverage of 1–3x (considered as low coverage). With merging of the reads from four libraries 1.06 % had zero and 1.75 % had 1–3x coverage. Right panel: Similarly, the proportion of the exome with zero coverage (gray color) or with 1–3x coverage (orange color) is shown