Comprehensive analysis of geographic and breed-purpose influences on genetic diversity and inherited disease risk in the Doberman dog breed

Table 3 Effective population sizes for locale-purpose cohorts based on sample size adjusted inter-chromosomal linkage-disequilibrium

Locale-purpose	DNA Cluster	Cluster Size	Mean ^a r²	Ne
All	Global	3,226	0.0079	44
Europe exhibition	0	886	0.0030	177
Informal	1	386	0.0063	89
Europe working	2	561	0.0065	70
Europe working (refined)^b	2A	309	0.0078	72
Americas exhibition	3	768	0.0034	158
Americas exhibition (refined)^c	3A	687	0.0036	155
Americas informal	4	625	0.0030	236

^aAdjusted for cohort sample size [8]
^bRetaining individuals with C1 < -0.05, C2 < 0 from multidimensional scaling after unsupervised clustering
^cRetaining individuals with C1 > 0.09 from multidimensional scaling after unsupervised clustering to exclude samples originating in Oceania

ISSN: 2662-9380