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Table 2 Risk factors for mast cell tumour (MCT) from univariable analysis

From: Prevalence and risk factors for mast cell tumours in dogs in England

Variable Category Case Control OR 95% CI P-value
Age ≤2.0 years 8 840 1(base)   <0.001
  2.0-4.0 years 22 301 7.7 3.4-17.4 <0.001
  4.0-6.0 years 60 245 25.7 12.1-54.5    0.038
  6.0-8.0 years 82 199 43.3 20.-90.9 <0.001
  8.0-10.0 years 95 171 58.3 27.8-122.3 <0.001
  >10.0 years 108 267 42.5 20.4-88.2 <0.001
Age (continuous) Median (IQR) (years) 8.2 (6.0 - 10.2) 3.1 (0.5 – 7.2 1.2 1.2-1.3 <0.001
Breed Type Crossbred 65 391 1(base)      0.016
  Boxer 47 22 12.9 7.3-22.7 <0.001
  Golden Retriever 43 39 6.6 4.0-11.0 <0.001
  Weimaraner 6 9 4.0 1.4-11.6    0.028
  Labrador Retriever 106 215 3.0 2.1-4.2 <0.001
  Pug 7 15 2.8 1.1-7.2    0.096
  Staffordshire Bull Terrier 72 159 2.7 1.9-4.0 <0.001
  Springer Spaniel 8 50 1.0 0.4-2.1    0.379
  Jack Russell Terrier 18 155 0.7 0.4-1.2    0.006
  Border Collie 3 60 0.3 0.1-1.0    0.005
  Cocker Spaniel 4 86 0.3 0.1-0.8    0.001
  West Highland White Terrier 3 66 0.3 0.1-0.9    0.002
  Yorkshire Terrier 2 57 0.2 0.1-0.9    0.003
  German Shepherd Dog 1 63 0.1 0.0-0.7 <0.001
  Other specific breed type 68 649 0.6 0.4-0.9    0.456
Purebred status Crossbred 65 391 1(base)   
  Of breed type 388 1654 1.4 1.1-1.9    0.016
Insurance status Not insured 162 1502 1(base)   
  Insured 291 527 5.1 4.1-6.4 <0.001
Neuter status Entire 130 102 1(base)   
  Neutered 323 820 0.3 0.2-0.4 <0.001
Sex Female 233 956 1(base)   
  Male 218 1067 1.2 1.0-1.5    0.090
Weight ≤10.0 kg 49 771 1(base)   <0.001
  10.0-20.0 kg 60 379 2.5 1.7-3.7 <0.001
  20.0-30.0 kg 145 296 7.7 5.4-10.9 <0.001
  30.0-40.0 kg 135 197 10.8 7.5-15.5 <0.001
  >40.0 kg 46 79 9.2 5.8-14.6 <0.001
Weight (continuous) (kg) Median (IQR) 27.7 (20.0 - 34.2) 11.6 (6.0 – 24.7) 1.1 1.1-1.1 <0.001
  1. Odds ratios (OR) with 95% confidence intervals (CI) are reported. Cases (n = 453) and controls (n = 2036) were selected from a VetCompass population of 168,636 dogs.