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Table 3 Variations in coding and flanking regions in candidate genes with corresponding physical positions according to the reference sequence

From: Homozygosity mapping and sequencing identify two genes that might contribute to pointing behavior in hunting dogs

 

Gene

Chromosome

Position

Reference sequence

Variation

Amino acid exchanges/ non-coding regions

rs number (build 131)

Pointing vs. herding dogs

RCBTB1

22

   

3′UTR

 

RCBTB1

22

5154333

T

C

F > F

rs23035959

PHF11

22

   

3′UTR

 

SETDB2

22

   

5′UTR

 

SETDB2

22

5213748

C

T

S #> N

rs23066192

SETDB2

22

   

3′UTR

 

CDADC1

22

5391565

C

T

V > V

-

CDADC1

22

   

3′UTR

 

MLNR

22

5451915

G

C

V > V

rs23039274

FNDC3A

22

   

3′UTR

 

CYSLTR2

22

   

5′UTR

 

CYSLTR2

22

5859501

A

G

L > L

rs23041728

CYSLTR2

22

5860286

C

G

P > R #

rs23041730

RSPO2

13

   

5′UTR

 

Herding vs. pointing dogs

RSPO2

13

   

3′UTR

 

TMEM74

13

   

5′UTR

 

TMEM74

13

   

3′UTR

 
  1. Corresponding rs identifiers for the sequence variations are listed if available. Sequence variations resulting in amino acid substitutions are indicated in bold. # = The amino acid present in pointing dogs. (Reference sequences from UCSC genome browser, May 2005; Broad/canFam2)