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Table 2 DLA-DQB1 allele combinations in Cocker spaniels with (cases) and without (controls) IMHA

From: Analysis of DLA-DQB1 and polymorphisms in CTLA4 in Cocker spaniels affected with immune-mediated haemolytic anaemia

DQB1* allele combination

Cases (n = 29 dogs)

Cases (frequency)

Controls (n = 63 dogs)

Controls (frequency)

P value

007:01*002:01

1

0.034

1

0.016

0.533

007:01*007:01

14

0.483

23

0.365

0.361

007:01*lk007cs

2

0.069

5

0.080

1.000

007:01*012:01

1

0.034

3

0.048

1.000

007:01*013:03

2

0.069

2

0.032

0.588

007:01*020:01

5

0.172

18

0.286

0.306

007:01*020:02

0

0

2

0.032

1.000

007:01*021:01

1

0.034

2

0.032

1.000

007:01*08:01:1

1

0.034

2

0.032

1.000

012:01*020:01

0

0

2

0.032

1.000

020:01*013:02

0

0

1

0.016

1.000

020:01*020:01

1

0.034

1

0.016

0.533

020:01*020:02

0

0

1

0.016

1.000

020:02*023:01

1

0.034

0

0

0.315

Homozygous

15

0.517

24

0.381

0.260

Heterozygous

14

0.483

39

0.619

0.260