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Table 2 DLA-DQB1 allele combinations in Cocker spaniels with (cases) and without (controls) IMHA

From: Analysis of DLA-DQB1 and polymorphisms in CTLA4 in Cocker spaniels affected with immune-mediated haemolytic anaemia

DQB1* allele combination Cases (n = 29 dogs) Cases (frequency) Controls (n = 63 dogs) Controls (frequency) P value
007:01*002:01 1 0.034 1 0.016 0.533
007:01*007:01 14 0.483 23 0.365 0.361
007:01*lk007cs 2 0.069 5 0.080 1.000
007:01*012:01 1 0.034 3 0.048 1.000
007:01*013:03 2 0.069 2 0.032 0.588
007:01*020:01 5 0.172 18 0.286 0.306
007:01*020:02 0 0 2 0.032 1.000
007:01*021:01 1 0.034 2 0.032 1.000
007:01*08:01:1 1 0.034 2 0.032 1.000
012:01*020:01 0 0 2 0.032 1.000
020:01*013:02 0 0 1 0.016 1.000
020:01*020:01 1 0.034 1 0.016 0.533
020:01*020:02 0 0 1 0.016 1.000
020:02*023:01 1 0.034 0 0 0.315
Homozygous 15 0.517 24 0.381 0.260
Heterozygous 14 0.483 39 0.619 0.260