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Table 5 CTLA4 promoter genotype frequency in Cocker spaniels with (cases) and without (controls) IMHA

From: Analysis of DLA-DQB1 and polymorphisms in CTLA4 in Cocker spaniels affected with immune-mediated haemolytic anaemia

Genotype Cases (n = 29 dogs) Cases (frequency) Controls (n = 63 dogs) Controls (frequency) P value
8/2 0 0.000 2 0.032 1.000
8/3 1 0.034 6 0.095 0.426
8/8 27 0.931 52 0.825 0.215
8/12 1 0.034 2 0.032 1.000
8/15 0 0.000 1 0.016 1.000
Homozygous 27 0.931 52 0.825 0.215
Heterozygous 2 0.069 11 0.175 0.215