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Table 2 Odds ratios of inherited disorders between purebred dog categories and the mixed-breed dog population diagnosed over a 15-year period

From: Ten inherited disorders in purebred dogs by functional breed groupings

 

OR (CI)

P value

No.

OR (CI)

P value

No.

OR (CI)

P value

No.

OR (CI)

P value

No.

OR (CI)

P value

No.

 

Aortic stenosis

Atopy/allergic dermatitis

Gastric dilatation volvulus

Early onset cataracts

Dilated cardiomyopathy

AKC Group

 Herding

2.25(1.25–4.05)

0.02

44

1.06(0.79–1.43)

0.58

0

1.63(0.83–3.23)

0.23

9

0.99(0.82–1.20)

0.67

0

0.73(0.34–1.56)

0.45

0

 Hound

1.50(0.66–3.45)

0.41

4

1.20(0.82–1.76)

0.14

2

2.72(1.01–7.34)

0.09

37

0.83(0.66–1.03)

0.13

15

4.98(2.29–10.83)

0.00

50

 Non-sporting

2.00(0.98–4.08)

0.09

26

2.49(1.83–3.38)

0.00

50

3.45(1.51–7.88)

0.01

46

1.72(1.44–2.06)

0.00

50

0.91(0.34–2.39)

0.63

0

 Sporting

2.10(1.25–3.52)

0.02

45

1.71(1.35–2.16)

0.00

50

1.20(0.67–2.14)

0.52

0

1.61(1.38–1.87)

0.00

50

2.40(1.45–3.97)

0.00

50

 Terrier

2.02(0.84–4.87)

0.19

13

2.98(2.11–4.21)

0.00

50

1.33(0.33–5.38)

0.60

0

0.95(0.78–1.15)

0.52

0

0.86(0.24–3.08)

0.58

0

 Toy

1.81(0.81–4.09)

0.22

7

1.76(1.23–2.47)

0.01

46

0.90(0.14–5.73)

0.20

0

1.16(0.98–1.37)

0.13

21

0.66(0.14–3.07)

0.56

0

 Working

6.26(3.74–10.45)

0.00

50

0.96(0.71–1.31)

0.65

0

2.45(1.34–4.48)

0.01

48

1.23(1.00–1.52)

0.11

24

11.60(6.87–19.50)

0.00

50

Haplotype group

 Ancient and spitz

1.49(0.58–3.79)

0.44

0

1.15(0.71–1.85)

0.56

1

2.27(0.87–5.91)

0.15

16

1.35(1.02–1.79)

0.08

26

1.88(0.77–4.60)

0.25

6

 Herding

1.17(0.48–2.89)

0.59

0

0.97(0.65–1.47)

0.61

0

0.29(0.06–1.42)

0.16

11

0.91(0.72–1.15)

0.45

0

0.26(0.06–1.19)

0.09

12

 Mastiff-like

8.30(4.59–15.02)

0.00

50

2.11(1.50–2.97)

0.00

50

1.42(0.58–3.50)

0.49

4

1.44(1.15–1.81)

0.01

48

7.24(3.76–13.95)

0.00

50

 Retriever

3.76(2.27–6.23)

0.00

50

(1.22–2.02)

0.01

49

1.63(0.93–2.85)

1.15

16

1.26(1.05–1.51)

0.05

38

3.22(.195–5.32)

0.00

50

 Scent hound

0.92(0.24–3.53)

0.63

0

1.46(0.92–2.30)

0.18

16

2.27(0.38–13.49)

0.43

0

0.93(0.73–1.19)

0.54

0

0.90(0.16–4.94)

0.68

0

 Sight hound

2.77(0.61–12.55)

0.28

3

0.47(0.15–1.48)

0.22

3

4.16(0.81–21.45)

0.16

15

0.55(0.28–1.08)

0.13

19

14.72(3.88–55.84)

0.00

50

 Small terrier

0.51(0.09–3.03)

0.45

0

3.86(2.45–6.08)

0.00

50

0.71(0.04–13.40)

0.72

0

0.87(0.67–1.12)

0.33

2

1.95(0.22–17.08)

0.62

0

 Spaniel

0.57(0.17–1.93)

0.38

0

1.57(1.07–2.32)

0.06

35

1.94(0.65–5.74)

0.32

3

1.88(1.54–2.30)

0.00

50

6.01(2.72–13.28)

0.00

50

 Toy

1.91(0.74–4.93)

0.25

8

1.62(1.07–2.44)

0.05

35

0.52(0.03–8.73)

0.63

0

0.88(0.72–1.09)

0.30

6

1.13(0.15–8.26)

0.62

0

 Working group 1

0.56(0.04–9.54)

0.98

0

1.75(0.98–3.13)

0.12

21

80.03(1.93–13.45)

0.04

47

2.17(1.65–2.85)

0.00

50

1.78(0.38–8.37)

0.53

0

 Working group 2

2.45(1.24–4.)

0.03

43

1.26(.087–1.83)

0.29

5

3.40(1.65–7.04)

0.01

48

0.89(0.67–1.18)

0.43

2

7.42(4.08–13.50)

0.00

50

 

Elbow dysplasia

Epilepsy

Hypothyroidism

IVDD

Portosystemic shunt

AKC group

 Herding

1.65(1.23–2.21)

0.00

48

1.57(1.14–2–2.16)

0.02

44

1.11(0.86–1.42)

0.46

1

1.53(1.31–1.79)

0.00

50

0.86(0.49–1.53)

0.56

0

 Hound

0.76(0.43–1.43)

0.40

2

1.65(1.09–2.50)

0.05

38

1.53(1.09–2.13)

0.04

37

4.54(3.82–5.40)

0.00

50

1.12(0.62–1.93)

0.59

0

 Non-sporting

0.72(0.45–1.16)

0.23

7

1.49(1.02–2.17)

0.08

31

1.43(1.06–1.92)

0.04

37

1.31(1.10–1.56)

0.01

48

0.80(0.47–1.38)

0.46

3

 Sporting

2.25(1.79–2.82)

0.00

50

1.51(1.15–1.98)

0.02

45

1.69(1.40–2.06)

0.00

50

0.93(0.81–1.07)

0.37

2

1.43(0.90–2.28)

0.21

14

 Terrier

1.37(0.74–2.55)

0.37

1

0.93(0.58–1.50)

0.56

1

1.18(0.82–1.70)

0.43

4

0.57(0.46–0.71)

0.00

50

2.00(1.27–3.13)

0.01

46

 Toy

0.67(0.19–2–40)

0.52

1

1.50(1.01–2.24)

0.09

26

1.31(0.91–1.88)

0.21

11

0.99(0.84–1.18)

0.65

0

4.15(2.89–5.96)

0.00

50

 Working

2.89(2.25–3.70)

0.00

50

0.80(0.55–1.15)

0.28

5

2.17(1.72–2.74)

0.00

50

1.78(1.51–2.09)

0.00

50

1.00(0.56–1.80)

0.68

0

Haplotype group

 Ancient and spitz

1.07(0.64–1.76)

0.64

0

1.30(.077–2.19)

0.41

3

2.00(1.41–2.84)

0.00

50

0.97(0.75–1.27)

0.64

0

1.24(0.47–3.21)

0.59

0

 Herding

0.71(0.42–1.20)

0.26

3

1.97(1.32–2.92)

0.00

49

1.30(0.93–1.79)

0.18

16

1.01(0.82–1.25)

0.66

0

1.06(0.56–2.00)

0.64

0

 Mastiff-like

1.17(0.80–1.72)

0.46

2

1.15(0.75–1.78)

0.48

1

1.21(0.86–1.71)

0.37

6

1.21(0.99–1.48)

1.10

23

0.81(0.46–1.43)

48

0

 Retriever

3.24(2.60–4.03)

0.00

50

1.21(0.90–1.63)

0.25

5

1.62(1.32–1.99)

0.00

50

1.11(0.96–1.29)

0.25

12

1.41(0.85–2.35)

0.25

4

 Scent hound

1.00(0.40–2.49)

0.65

0

1.99(1.22–3.25)

0.02

45

1.61(1.05–2.47)

0.06

28

6.33(5.22–7.68)

0.00

50

1.04(0.57–1.87)

0.68

0

 Sight hound

0.15(0.02–1.13)

0.08

17

1.51(0.59–3.88)

0.45

2

1.11(0.51–2.42)

0.62

0

1.39(0.91–2.13)

0.20

9

1.89(0.55–6.58)

0.36

0

 Small terrier

0.28(0.02–3.66)

0.44

1

0.93(0.48–1.79)

0.62

0

1.23(0.70–2.17)

0.51

2

0.51(0.38–0.70)

0.00

50

6.90(4.36–10.93)

0.00

50

 Spaniel

0.57(0.29–1.11)

0.15

16

1.81(1.20–2.73)

0.02

46

1.76(1.27–2.43)

0.01

49

0.88(0.71–1.09)

0.28

2

0.76(0.40–1.55)

0.48

0

 Toy

0.40(0.6–2.80)

0.37

0

1.42(0.89–2.26)

0.22

14

1.22(0.77–1.93)

0.44

4

1.24(1.51)

0.07

32

2.92(1.95–4.38)

0.00

50

 Working group 1

0.30(0.08–1.06)

0.09

22

2.54(1.40–4.61)

0.01

48

1.26(0.72–2.20)

0.47

2

1.19(0.88–1.61)

0.33

3

2.23(1.14–4.37)

0.05

35

 Working group 2

1.88(1.35–2.30)

0.00

50

1.40(0.91–2.15)

0.20

10

1.49(1.09–2.02)

0.04

40

2.51(2.07–3.03)

0.00

50

0.74(0.29–1.88)

0.53

0