From: Ten inherited disorders in purebred dogs by functional breed groupings
 | OR (CI) | P value | No. | OR (CI) | P value | No. | OR (CI) | P value | No. | OR (CI) | P value | No. | OR (CI) | P value | No. |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Aortic stenosis | Atopy/allergic dermatitis | Gastric dilatation volvulus | Early onset cataracts | Dilated cardiomyopathy | ||||||||||
AKC Group | |||||||||||||||
 Herding | 2.25(1.25–4.05) | 0.02 | 44 | 1.06(0.79–1.43) | 0.58 | 0 | 1.63(0.83–3.23) | 0.23 | 9 | 0.99(0.82–1.20) | 0.67 | 0 | 0.73(0.34–1.56) | 0.45 | 0 |
 Hound | 1.50(0.66–3.45) | 0.41 | 4 | 1.20(0.82–1.76) | 0.14 | 2 | 2.72(1.01–7.34) | 0.09 | 37 | 0.83(0.66–1.03) | 0.13 | 15 | 4.98(2.29–10.83) | 0.00 | 50 |
 Non-sporting | 2.00(0.98–4.08) | 0.09 | 26 | 2.49(1.83–3.38) | 0.00 | 50 | 3.45(1.51–7.88) | 0.01 | 46 | 1.72(1.44–2.06) | 0.00 | 50 | 0.91(0.34–2.39) | 0.63 | 0 |
 Sporting | 2.10(1.25–3.52) | 0.02 | 45 | 1.71(1.35–2.16) | 0.00 | 50 | 1.20(0.67–2.14) | 0.52 | 0 | 1.61(1.38–1.87) | 0.00 | 50 | 2.40(1.45–3.97) | 0.00 | 50 |
 Terrier | 2.02(0.84–4.87) | 0.19 | 13 | 2.98(2.11–4.21) | 0.00 | 50 | 1.33(0.33–5.38) | 0.60 | 0 | 0.95(0.78–1.15) | 0.52 | 0 | 0.86(0.24–3.08) | 0.58 | 0 |
 Toy | 1.81(0.81–4.09) | 0.22 | 7 | 1.76(1.23–2.47) | 0.01 | 46 | 0.90(0.14–5.73) | 0.20 | 0 | 1.16(0.98–1.37) | 0.13 | 21 | 0.66(0.14–3.07) | 0.56 | 0 |
 Working | 6.26(3.74–10.45) | 0.00 | 50 | 0.96(0.71–1.31) | 0.65 | 0 | 2.45(1.34–4.48) | 0.01 | 48 | 1.23(1.00–1.52) | 0.11 | 24 | 11.60(6.87–19.50) | 0.00 | 50 |
Haplotype group | |||||||||||||||
 Ancient and spitz | 1.49(0.58–3.79) | 0.44 | 0 | 1.15(0.71–1.85) | 0.56 | 1 | 2.27(0.87–5.91) | 0.15 | 16 | 1.35(1.02–1.79) | 0.08 | 26 | 1.88(0.77–4.60) | 0.25 | 6 |
 Herding | 1.17(0.48–2.89) | 0.59 | 0 | 0.97(0.65–1.47) | 0.61 | 0 | 0.29(0.06–1.42) | 0.16 | 11 | 0.91(0.72–1.15) | 0.45 | 0 | 0.26(0.06–1.19) | 0.09 | 12 |
 Mastiff-like | 8.30(4.59–15.02) | 0.00 | 50 | 2.11(1.50–2.97) | 0.00 | 50 | 1.42(0.58–3.50) | 0.49 | 4 | 1.44(1.15–1.81) | 0.01 | 48 | 7.24(3.76–13.95) | 0.00 | 50 |
 Retriever | 3.76(2.27–6.23) | 0.00 | 50 | (1.22–2.02) | 0.01 | 49 | 1.63(0.93–2.85) | 1.15 | 16 | 1.26(1.05–1.51) | 0.05 | 38 | 3.22(.195–5.32) | 0.00 | 50 |
 Scent hound | 0.92(0.24–3.53) | 0.63 | 0 | 1.46(0.92–2.30) | 0.18 | 16 | 2.27(0.38–13.49) | 0.43 | 0 | 0.93(0.73–1.19) | 0.54 | 0 | 0.90(0.16–4.94) | 0.68 | 0 |
 Sight hound | 2.77(0.61–12.55) | 0.28 | 3 | 0.47(0.15–1.48) | 0.22 | 3 | 4.16(0.81–21.45) | 0.16 | 15 | 0.55(0.28–1.08) | 0.13 | 19 | 14.72(3.88–55.84) | 0.00 | 50 |
 Small terrier | 0.51(0.09–3.03) | 0.45 | 0 | 3.86(2.45–6.08) | 0.00 | 50 | 0.71(0.04–13.40) | 0.72 | 0 | 0.87(0.67–1.12) | 0.33 | 2 | 1.95(0.22–17.08) | 0.62 | 0 |
 Spaniel | 0.57(0.17–1.93) | 0.38 | 0 | 1.57(1.07–2.32) | 0.06 | 35 | 1.94(0.65–5.74) | 0.32 | 3 | 1.88(1.54–2.30) | 0.00 | 50 | 6.01(2.72–13.28) | 0.00 | 50 |
 Toy | 1.91(0.74–4.93) | 0.25 | 8 | 1.62(1.07–2.44) | 0.05 | 35 | 0.52(0.03–8.73) | 0.63 | 0 | 0.88(0.72–1.09) | 0.30 | 6 | 1.13(0.15–8.26) | 0.62 | 0 |
 Working group 1 | 0.56(0.04–9.54) | 0.98 | 0 | 1.75(0.98–3.13) | 0.12 | 21 | 80.03(1.93–13.45) | 0.04 | 47 | 2.17(1.65–2.85) | 0.00 | 50 | 1.78(0.38–8.37) | 0.53 | 0 |
 Working group 2 | 2.45(1.24–4.) | 0.03 | 43 | 1.26(.087–1.83) | 0.29 | 5 | 3.40(1.65–7.04) | 0.01 | 48 | 0.89(0.67–1.18) | 0.43 | 2 | 7.42(4.08–13.50) | 0.00 | 50 |
 | Elbow dysplasia | Epilepsy | Hypothyroidism | IVDD | Portosystemic shunt | ||||||||||
AKC group | |||||||||||||||
 Herding | 1.65(1.23–2.21) | 0.00 | 48 | 1.57(1.14–2–2.16) | 0.02 | 44 | 1.11(0.86–1.42) | 0.46 | 1 | 1.53(1.31–1.79) | 0.00 | 50 | 0.86(0.49–1.53) | 0.56 | 0 |
 Hound | 0.76(0.43–1.43) | 0.40 | 2 | 1.65(1.09–2.50) | 0.05 | 38 | 1.53(1.09–2.13) | 0.04 | 37 | 4.54(3.82–5.40) | 0.00 | 50 | 1.12(0.62–1.93) | 0.59 | 0 |
 Non-sporting | 0.72(0.45–1.16) | 0.23 | 7 | 1.49(1.02–2.17) | 0.08 | 31 | 1.43(1.06–1.92) | 0.04 | 37 | 1.31(1.10–1.56) | 0.01 | 48 | 0.80(0.47–1.38) | 0.46 | 3 |
 Sporting | 2.25(1.79–2.82) | 0.00 | 50 | 1.51(1.15–1.98) | 0.02 | 45 | 1.69(1.40–2.06) | 0.00 | 50 | 0.93(0.81–1.07) | 0.37 | 2 | 1.43(0.90–2.28) | 0.21 | 14 |
 Terrier | 1.37(0.74–2.55) | 0.37 | 1 | 0.93(0.58–1.50) | 0.56 | 1 | 1.18(0.82–1.70) | 0.43 | 4 | 0.57(0.46–0.71) | 0.00 | 50 | 2.00(1.27–3.13) | 0.01 | 46 |
 Toy | 0.67(0.19–2–40) | 0.52 | 1 | 1.50(1.01–2.24) | 0.09 | 26 | 1.31(0.91–1.88) | 0.21 | 11 | 0.99(0.84–1.18) | 0.65 | 0 | 4.15(2.89–5.96) | 0.00 | 50 |
 Working | 2.89(2.25–3.70) | 0.00 | 50 | 0.80(0.55–1.15) | 0.28 | 5 | 2.17(1.72–2.74) | 0.00 | 50 | 1.78(1.51–2.09) | 0.00 | 50 | 1.00(0.56–1.80) | 0.68 | 0 |
Haplotype group | |||||||||||||||
 Ancient and spitz | 1.07(0.64–1.76) | 0.64 | 0 | 1.30(.077–2.19) | 0.41 | 3 | 2.00(1.41–2.84) | 0.00 | 50 | 0.97(0.75–1.27) | 0.64 | 0 | 1.24(0.47–3.21) | 0.59 | 0 |
 Herding | 0.71(0.42–1.20) | 0.26 | 3 | 1.97(1.32–2.92) | 0.00 | 49 | 1.30(0.93–1.79) | 0.18 | 16 | 1.01(0.82–1.25) | 0.66 | 0 | 1.06(0.56–2.00) | 0.64 | 0 |
 Mastiff-like | 1.17(0.80–1.72) | 0.46 | 2 | 1.15(0.75–1.78) | 0.48 | 1 | 1.21(0.86–1.71) | 0.37 | 6 | 1.21(0.99–1.48) | 1.10 | 23 | 0.81(0.46–1.43) | 48 | 0 |
 Retriever | 3.24(2.60–4.03) | 0.00 | 50 | 1.21(0.90–1.63) | 0.25 | 5 | 1.62(1.32–1.99) | 0.00 | 50 | 1.11(0.96–1.29) | 0.25 | 12 | 1.41(0.85–2.35) | 0.25 | 4 |
 Scent hound | 1.00(0.40–2.49) | 0.65 | 0 | 1.99(1.22–3.25) | 0.02 | 45 | 1.61(1.05–2.47) | 0.06 | 28 | 6.33(5.22–7.68) | 0.00 | 50 | 1.04(0.57–1.87) | 0.68 | 0 |
 Sight hound | 0.15(0.02–1.13) | 0.08 | 17 | 1.51(0.59–3.88) | 0.45 | 2 | 1.11(0.51–2.42) | 0.62 | 0 | 1.39(0.91–2.13) | 0.20 | 9 | 1.89(0.55–6.58) | 0.36 | 0 |
 Small terrier | 0.28(0.02–3.66) | 0.44 | 1 | 0.93(0.48–1.79) | 0.62 | 0 | 1.23(0.70–2.17) | 0.51 | 2 | 0.51(0.38–0.70) | 0.00 | 50 | 6.90(4.36–10.93) | 0.00 | 50 |
 Spaniel | 0.57(0.29–1.11) | 0.15 | 16 | 1.81(1.20–2.73) | 0.02 | 46 | 1.76(1.27–2.43) | 0.01 | 49 | 0.88(0.71–1.09) | 0.28 | 2 | 0.76(0.40–1.55) | 0.48 | 0 |
 Toy | 0.40(0.6–2.80) | 0.37 | 0 | 1.42(0.89–2.26) | 0.22 | 14 | 1.22(0.77–1.93) | 0.44 | 4 | 1.24(1.51) | 0.07 | 32 | 2.92(1.95–4.38) | 0.00 | 50 |
 Working group 1 | 0.30(0.08–1.06) | 0.09 | 22 | 2.54(1.40–4.61) | 0.01 | 48 | 1.26(0.72–2.20) | 0.47 | 2 | 1.19(0.88–1.61) | 0.33 | 3 | 2.23(1.14–4.37) | 0.05 | 35 |
 Working group 2 | 1.88(1.35–2.30) | 0.00 | 50 | 1.40(0.91–2.15) | 0.20 | 10 | 1.49(1.09–2.02) | 0.04 | 40 | 2.51(2.07–3.03) | 0.00 | 50 | 0.74(0.29–1.88) | 0.53 | 0 |