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Table 2 DLA haplotypes in the Gordon setter

From: Genetics and epidemiology of hypothyroidism and symmetrical onychomadesis in the Gordon setter and the English setter

 

All GS

GS cases

GS controls

GS cases/ GS controls

DLA-haplotype

%

n = 322

%

n = 136

%

n = 186

OR

CI 95 %

p-value

DRB1*01801/DQA1*00101/DQB1*00802

31.9

103

18.3

25

41.9

78

0.3

0.2-0.5

0.000006

DRB1*01501/DQA1*00601/DQB1*02301

5.9

19

2.2

3

8.6

16

0.2

0.1-0.8

0.001

DRB1*00103/DQA1*00101/DQB1*00201

8.3

27

14.7

20

3.7

7

4.4

1.8-11.5

0.0005

DRB1*00101/DQA1*00101/DQB1*00201

11.1

36

15.4

21

8.0

15

2.1

1.03-4.28

0.04

DRB1*02001/DQA1*00401/DQB1*01303

11.4

37

11.0

15

11.8

22

n.s

  

DRB1*04901/DQA1*01001/DQB1*01901

18.9

61

25.7

35

13.9

26

2.1

1.2-3.7

0.008

DRB1*00901/DQA1*00101/DQB1*008011

7.4

24

6.6

9

8.0

15

n.s

  

DRB1*00501/DQA1*00301/DQB1*00501

0.9

3

1.4

2

0.5

1

n.s

  

DRB1*00107/DQA1*00101/DQB1*00201

1.8

6

3.6

5

0.5

1

n.s

  

DRB1*01501/DQA1*00601/DQB1*00301

1.8

6

0.7

1

2.6

5

n.s

  
  1. Cases; Gordon setter with hypothyroidism, Controls; Gordon setters without hypothyroidism, n.s; non significant, OR; Odd ratio, CI; confidence interval
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Canine Medicine and Genetics

ISSN: 2662-9380