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Table 5 DLA-haplotypes and alleles associated with hypothyroidism or protection against hypothyroidism in the English setter

From: Genetics and epidemiology of hypothyroidism and symmetrical onychomadesis in the Gordon setter and the English setter

  Total Cases Controls Cases/Controls
DLA-haplotype or allele % n = 272 % n = 166 % n = 106 OR CI 95 % p-value
DRB1*00107/DQA1*00101/DQB1*00201 24.6 67 29.5 49 17.0 18 2.0 1.1-3.8 0.01
DLA-DQA1*00101 89.3 243 93.4 155 83.0 88 2.9 1.3-6.6 0.002
DLA-DQB1*00201 77.6 211 81.9 136 70.8 75 1.9 1.1-3.3 0.03
DRB1*00601/DQA1*005011/DQB1*00701 3.3 9 1.2 2 6.6 7 0.2 0.03-0.8 0.02