Table 5 DLA-haplotypes and alleles associated with hypothyroidism or protection against hypothyroidism in the English setter
Total | Cases | Controls | Cases/Controls | ||||||
|---|---|---|---|---|---|---|---|---|---|
DLA-haplotype or allele | % | n = 272 | % | n = 166 | % | n = 106 | OR | CI 95 % | p-value |
DRB1*00107/DQA1*00101/DQB1*00201 | 24.6 | 67 | 29.5 | 49 | 17.0 | 18 | 2.0 | 1.1-3.8 | 0.01 |
DLA-DQA1*00101 | 89.3 | 243 | 93.4 | 155 | 83.0 | 88 | 2.9 | 1.3-6.6 | 0.002 |
DLA-DQB1*00201 | 77.6 | 211 | 81.9 | 136 | 70.8 | 75 | 1.9 | 1.1-3.3 | 0.03 |
DRB1*00601/DQA1*005011/DQB1*00701 | 3.3 | 9 | 1.2 | 2 | 6.6 | 7 | 0.2 | 0.03-0.8 | 0.02 |