Fig. 6

(Upper) Manhattan plot of GWAS using seven Samoyed with enamel hypoplasia five unrelated healthy controls showing a genome-wide association on CFA 8. (Lower) Allele frequency in the 12-Mb region of CFA 8 for enamel hypoplasia (solid diamond) and control (open circle) and the location of a known candidate SLC24A4 for a form of autosomal recessive amelogenesis imperfecta in humans