TY - JOUR AU - Keijser, S. F. A. AU - Fieten, H. AU - Vos-Loohuis, M. AU - Piek, C. J. AU - Anderson, H. AU - Donner, J. AU - Scholten, I. AU - Nielen, M. AU - Hesselink, J. W. AU - van Steenbeek, F. G. PY - 2018 DA - 2018/12/28 TI - Heterozygosity testing and multiplex DNA panel screening as a potential tool to monitor health and inbreeding in a small, closed dog population JO - Canine Genetics and Epidemiology SP - 12 VL - 5 IS - 1 AB - Selective breeding in populations with a limited effective population size may result in a loss of genetic diversity, which can cause an increased concentration of specific disease liability genes. The Dutch Shepherd Dog (DSD) in the Netherlands is an example of such a breed with a small effective population. SN - 2052-6687 UR - https://doi.org/10.1186/s40575-018-0068-6 DO - 10.1186/s40575-018-0068-6 ID - Keijser2018 ER -