Table 3 DLA class II genotypes significantly associated with Addison’s disease (AD) and symmetrical lupoid onychodystrophy (SLO) in 233 Bearded collies, and corresponding odds ratios (OR) with the 95% confidence interval (CI) using the DLA haplotype codes reported in Table 2
Disease | Genotypes | Controls | Cases | p-value† | OR (95% CI) | ||
|---|---|---|---|---|---|---|---|
n | % | n | % | ||||
AD | All genotypes containing haplotype 1 | 23 | 18.9 | 23 | 37.7 | 0.0070 | 2.6 (1.31–5.19) |
AD | Genotype 1 5 | 7 | 5.7 | 11 | 18.0 | 0.0154 | 3.6 (1.32–9.87) |
SLO | All genotypes containing haplotype 4 | 62 | 50.8 | 36 | 72.0 | 0.0115 | 2.5 (1.22–5.07) |
SLO | All genotypes containing haplotype 5 | 59 | 48.4 | 35 | 70.0 | 0.0114 | 2.5 (1.24–5.02) |
SLO | Genotype 4 4 | 11 | 9.0 | 11 | 22.0 | 0.0258 | 2.8 (1.14–7.08) |
SLO | Genotype 5 5 | 11 | 9.0 | 11 | 22.0 | 0.0258 | 2.8 (1.14–7.08) |
SLO | Genotype 4 5 | 23 | 18.9 | 22 | 44.0 | 0.0011 | 3.4 (1.65–6.94) |
SLO | Genotypes containing haplotypes 4 and/or 5 | 98 | 80.3 | 49 | 98.0 | 0.0033 | 12.0 (1.58–91.33) |