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Table 6 Multivariable cox regression results

From: Diabetes mellitus in dogs attending UK primary-care practices: frequency, risk factors and survival

Variable Hazard Ratio
(n = 409)
95% CIa Category P-value Variable P-value
Age at diagnosis     < 0.001
 3 to < 8 years Base    
 8 to < 10 years 0.98 0.64–1.50 0.935  
 10 to < 13 years 2.12 1.42–3.18 < 0.001  
  > 13 years 2.02 1.17–3.49 0.011  
Neuter status     < 0.001
  Entire Base    
  Neutered 0.56 0.42–0.78 < 0.001  
Breed ≥ 5 dogs     0.050
 Cocker Spaniel 2.06 1.06–4.01 0.034  
 Staffordshire Bull Terrier 1.85 0.86–3.97 0.116  
 Border Terrier 1.19 0.68–2.10 0.543  
 Labrador Retriever 1.08 0.62–1.89 0.786  
 Purebred (other) 1.00 0.63–1.57 0.989  
 Crossbred Base    
 Miniature Schnauzer 0.96 0.41–2.25 0.925  
 Jack Russell Terrier 0.88 0.51–1.52 0.655  
 Cavalier King Charles Spaniel 0.86 0.40–1.84 0.690  
 Tibetan Terrier 0.72 0.28–1.84 0.489  
 Yorkshire Terrier 0.69 0.39–1.21 0.198  
 West Highland White Terrier 0.69 0.44–1.08 0.103  
 Cairn Terrier 0.56 0.13–2.37 0.432  
 Bichon Frise 0.46 0.18–1.16 0.101  
 Border Collie 0.39 0.17–0.87 0.022  
BG level at diagnosis     0.004
  < 20 mmol/L Base    
 20 to < 30 mmol/L 0.96 0.55–1.70 0.913  
 30 to < 40 mmol/L 1.52 0.88–2.65 0.137  
  > 40 mmol/L 2.75 1.35–5.57 0.005  
 No evidence/record of BG test 1.42 0.84–2.41 0.187  
Insulin treatment     < 0.001
 Insulin treatment started 0.08 0.05–0.12 < 0.001  
 No insulin treatment Base    
 Insulin treatment unknown . . .  
Glucocorticoid treatment 6 wks prior to diagnosis     0.008
 Yes 1.83 1.20–2.80 0.005  
 No Base    
Veterinary group     0.087
 A 2.12 0.26–17.38 0.488  
 B 0.75 0.56–1.02 0.063  
 C 1.35 0.91–2.02 0.137  
 D Base    
 E 1.64 0.39–6.99 0.501  
  1. Multivariable cox regression survival analysis for dogs 3 years and older diagnosed with diabetes mellitus at UK primary-care practices in 2016.
  2. a Confidence Interval