Fig. 3

Two-way repeated measured analysis of variance comparing leukocyte production of interleukin (IL)-6 between blood samples incubated in calcitriol (blue lines, n = 10) and control (red lines, n = 10) with subsequent exposure to phosphate buffered saline (PBS), lipopolysaccharide (LPS), or lipoteichoic acid (LTA). The black lines represent the mean, bars the SD, and the black circles are individual dog data. There was a significant between-pathogen associated molecular pattern (PAMP)-exposure difference (p < 0.001), but not a between-treatment difference (p = 0.12). There was not a treatment-by-PAMP exposure interaction (p = 0.07)