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Table 3 Odds Ratios (OR) and 95% confidence intervals (CI) for genotypes of the 3-SNP CFA 14 haplotype and the 2-SNP CFA 37 haplotype associated with idiopathic epilepsy. Not applicable (NA) reflects the inability to calculate the OR. The genotype associated with elevated risk for Belgian shepherds is indicated with an asterisk

From: Genome-wide association analysis of idiopathic epilepsy in the Belgian shepherd

Genotype for the significant CFA 14 SNPs BICF2P1043850/BICF2S23749130/TIGRP2P191770_rs9025240 Controls (n = 62) Cases (n = 35) OR (95% CI) p value
AA/AA/AA 46 9 0.12 (0.05–0.31) 0.000005
AG/AG/AC* 16 23 5.51 (2.24–13.56) 0.000201
GG/GG/CC 0 3 NA 0.044391
AA/AA/AA
vs
GG/GG/CC
46 9 NA 0.007130
0 3
AA/AA/AA
vs
AG/AG/AC*
46 9 0.14 (0.05–0.35) 0.000024
16 23
AG/AG/AC
vs
GG/GG/CC
16 23 NA 0.275261
0 3
Genotypes for the suggestive CFA 37 SNPs BICF2P271491/TIGRP2P419463_rs8724220 Controls (n = 62) Cases (n = 35) OR (95% CI) p value
AA/AA 12 1 0.12 (0.02–0.99) 0.028124
AG/AG 25 6 0.31 (0.11–0.84) 0.023494
GG/GG* 25 28 5.92 (2.24–15.62) 0.000249
AA/AA
vs
GG/GG*
12 1 0.07 (0.01–0.61) 0.004025
25 28
AA/AA
vs
AG/AG
12 1 0.35 (0.04–3.22) 0.419318
25 6
AG/AG
vs
GG/GG*
25 6 0.21 (0.08–0.61) 0.002890
25 28