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Table 3 Haplotype frequencies (%) observed for the six lowest risk breeds included in the study

From: Dog leucocyte antigen (DLA) class II haplotypes and risk of canine diabetes mellitus in specific dog breeds

Haplotype ID Haplotype Border Terrier Labrador Retriever Yorkshire Terrier CKCS Cocker Spaniel JRT
DRB1 DQA1 DQB1 Cases
n = 27 		Cntr
n = 27 		Cases
n = 111 		Cntr
n = 240 		Cases
n = 45 		Cntr
n = 45 		Cases
n = 48 		Cntr
n = 48 		Cases
n = 55 		Cntr
n = 80 		Cases
n = 49 		Cntr
n = 57
1 001:01 001:01 002:01    20.3 13.8        13.3 14.0
2 001:01 001:01 036:01            8.2 7.9
4 002:01 009:01 001:01 57.4 50.0    7.8 12.2      8.2 7.9
5 005:01 003:01 005:01 11.1 7.4     2.2      3.1 2.6
6 006:01 005:01:1 007:01    14.4 12.1 45.6 37.8 3.1 4.2 89.1 56.3 6.7 7.0
7 006:01 005:01:1 020:01    3.2 3.5    5.2   8.2 23.1   
8 008:02 003:01 004:01    3.2 3.5        2.0  
9 009:01 001:01 008:01:1        16.7 20.8    9.2 6.1
11 011:01 002:01 013:02 13.0           2.0 2.6
12 011:01 002:01 013:03        37.5 51.0   2.5   
14 012:01 004:01 017:01–013:03    26.6 32.7      0 5.0   
15 013:01 001:01 002:01      5.6       9.2 8.8
16 015:01 006:01 003:01            2.0 2.6
19 015:01 006:01 020:02 7.4 27.8    3.3 3.3    0 6.9 2.0  
20 015:01 006:01 022:01      3.3 7.8      7.1 4.4
21 015:01 006:01 023:01    7.7 9.0   3.3      5.1 7.0
25 015:02 006:01 023:01    13.5 14.4 15.6 16.7   3.1     3.5
26 018:01 001:01 002:01            2.0  
27 018:01 001:01 008:02 3.7           6.1 7.0
28 020:01 004:01 013:03    2.3 2.5    35.4 16.7     
29 023:01 003:01 005:01      4.4 4.4       
  001:01 002:01 036:01            2.0  
  001:02 001:01 002:01            2.0  
  002:02 009:01 001:01      4.4       2.0  
  005:01 009:01 023:01   3.7           
  006:01 005:01:1 028:01      6.7        
  008:03 003:01 004:01 3.7            
  012:01 004:01 013:03    2.7          
  017:01 002:01 013:03       2.2       
  020:01 004:01 013:01         2.1     
  075:01 004:01 013:03       2.2       
  1. Only haplotypes with a frequency > 2% are shown. Haplotypes which were significantly different between cases and controls in an individual breed are shown in bold. Haplotypes are sorted by haplotype ID, where these were assigned (Supplementary Table 2; assigned to the 30 most commonly observed haplotypes for ease of reference throughout the study). Breeds are listed in order of breed risk for DM, as indicated in Table 1. n = number of dogs, Cntr controls, CKCS Cavalier King Charles Spaniel, JRT Jack Russell Terrier
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Canine Medicine and Genetics

ISSN: 2662-9380