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Table 5 Combined analysis of all 12 breeds (only significant haplotypes shown)

From: Dog leucocyte antigen (DLA) class II haplotypes and risk of canine diabetes mellitus in specific dog breeds

Haplotype ID

Haplotype

Cases

%

Controls

%

Odds ratio

95% Confidence interval

Protective/Risk

DRB1

DQA1

DQB1

6

006:01

005:01:1

007:01

14.1

10.9

1.34

1.07–1.67

Risk

7

006:01

005:01:1

020:01

1.7

3.0

0.557

0.32–0.93

Protective

14

012:01

004:01

017:01–013:03

4.5

9.3

0.469

0.34–0.64

Protective

16

015:01

006:01

003:01

0.3

1.2

0.267

0.07–0.79

Protective

  1. DLA class II haplotypes significantly associated (upper and lower 95% confidence intervals did not cross 1) with diabetes mellitus in combined analysis with all breeds pooled together, calculated using Fisher’s exact test