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Fig. 2 | Canine Medicine and Genetics

Fig. 2

From: Comprehensive genetic testing combined with citizen science reveals a recently characterized ancient MC1R mutation associated with partial recessive red phenotypes in dog

Fig. 2

The eA allele associated domino pattern is recessive to the wild type E allele. Mating of recessive red (cream colored) e1/e1 sire to E/eA wolf sable dam in the Tamaskan Dog breed, resulting in four normal wolf sable puppies with E/e1 genotype and four puppies with domino pattern, of which two express domino on wolf sable and two express domino on recessive black. In newborns, domino pattern is visible as large pheomelanin colored areas on both sides of the muzzle, pheomelanin areas around the eyes and overall as a lighter coat color of the body with dark bar of hair remaining on the back side around the vertebra

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