From: Polymorphisms in the CTLA4 promoter sequence are associated with canine hypoadrenocorticism
Marker | Minor Allele | Group | Genotype frequency | Observed Heterozygotes | Expected Heterozygotes | P value |
---|---|---|---|---|---|---|
SNP1 | A | Case | 2–1 - 25 | 0.036 | 0.163 | 0.005 |
Control | 0–7 - 24 | 0.226 | 0.2 | 1 | ||
SNP2 | A | Case | 2–1 - 25 | 0.036 | 0.163 | 0.005 |
Control | 0–7 - 24 | 0.226 | 0.2 | 1 | ||
SNP3 | A | Case | 0–0 - 28 | 0 | 0 | 1 |
Control | 0–0 - 31 | 0 | 0 | 1 | ||
SNP4 | A | Case | 2–1 - 25 | 0.036 | 0.163 | 0.005 |
Control | 0–7 - 24 | 0.226 | 0.2 | 1 | ||
SNP5 | A | Case | 2–1 - 25 | 0.036 | 0.163 | 0.005 |
Control | 0–7 - 24 | 0.226 | 0.2 | 1 | ||
SNP6 | A | Case | 2–1 - 25 | 0.036 | 0.163 | 0.005 |
Control | 0–7 - 24 | 0.226 | 0.2 | 1 | ||
SNP7 | G | Case | 2–1 - 25 | 0.036 | 0.163 | 0.005 |
Control | 0–7 - 24 | 0.226 | 0.2 | 1 | ||
SNP8 | A | Case | 0–0 - 28 | 0 | 0 | 1 |
Control | 0–0 - 31 | 0 | 0 | 1 | ||
SNP9 | A | Case | 2–1 - 25 | 0.036 | 0.163 | 0.005 |
Control | 0–7 - 24 | 0.226 | 0.2 | 1 | ||
SNP10 | G | Case | 2–1 - 25 | 0.036 | 0.163 | 0.005 |
Control | 0–7 - 24 | 0.226 | 0.2 | 1 | ||
SNP11 | G | Case | 0–0 - 28 | 0 | 0 | 1 |
Control | 0–0 - 31 | 0 | 0 | 1 | ||
SNP12 | T | Case | 2–1 - 25 | 0.036 | 0.163 | 0.005 |
Control | 0–7 - 24 | 0.226 | 0.2 | 1 | ||
SNP13 | T | Case | 0–3 - 25 | 0.107 | 0.101 | 1 |
Control | 0–1 - 30 | 0.032 | 0.032 | 1 | ||
SNP14 | A | Case | 7–11 - 10 | 0.393 | 0.494 | 0.275 |
Control | 9–15 - 7 | 0.484 | 0.498 | 1 | ||
SNP15 | C | Case | 2–1 - 25 | 0.036 | 0.163 | 0.005 |
Control | 0–7 - 24 | 0.226 | 0.2 | 1 | ||
SNP16 | G | Case | 2–1 - 25 | 0.036 | 0.163 | 0.005 |
Control | 0–7 - 24 | 0.226 | 0.2 | 1 | ||
SNP17 | C | Case | 0–0 - 28 | 0 | 0 | 1 |
Control | 0–0 - 31 | 0 | 0 | 1 | ||
SNP18 | G | Case | 7–12 - 9 | 0.429 | 0.497 | 0.466 |
Control | 5–12 - 14 | 0.387 | 0.458 | 0.438 | ||
SNP19 | A | Case | 2–1 - 25 | 0.036 | 0.163 | 0.005 |
Control | 0–7 - 24 | 0.226 | 0.2 | 1 | ||
SNP20 | T | Case | 0–0 - 28 | 0 | 0 | 1 |
Control | 0–0 - 31 | 0 | 0 | 1 | ||
indel1 | – | Case | 0–0 - 28 | 0 | 0 | 1 |
Control | 0–0 - 31 | 0 | 0 | 1 | ||
indel2 | – | Case | 2–1 - 25 | 0.036 | 0.163 | 0.005 |
Control | 0–7 - 24 | 0.226 | 0.2 | 1 | ||
indel3 | + | Case | 2–4 - 22 | 0.143 | 0.245 | 0.066 |
Control | 0–8 - 23 | 0.258 | 0.225 | 1 |