Skip to main content

Table 3 Hardy Weinberg Equilibrium in WHWTs SNPs and indels are shown in 5’ to 3’ order top to bottom; 118 WHWT alleles counted for each marker with 100% call rate. Genotype frequencies are shown as homozygote for minor allele/heterozygote/homozygote for major allele. For significant deviation from Hardy Weinberg equilibrium the p value is highlighted in red

From: Polymorphisms in the CTLA4 promoter sequence are associated with canine hypoadrenocorticism

MarkerMinor AlleleGroupGenotype frequencyObserved HeterozygotesExpected HeterozygotesP value
SNP1ACase2–1 - 250.0360.1630.005
Control0–7 - 240.2260.21
SNP2ACase2–1 - 250.0360.1630.005
Control0–7 - 240.2260.21
SNP3ACase0–0 - 28001
Control0–0 - 31001
SNP4ACase2–1 - 250.0360.1630.005
Control0–7 - 240.2260.21
SNP5ACase2–1 - 250.0360.1630.005
Control0–7 - 240.2260.21
SNP6ACase2–1 - 250.0360.1630.005
Control0–7 - 240.2260.21
SNP7GCase2–1 - 250.0360.1630.005
Control0–7 - 240.2260.21
SNP8ACase0–0 - 28001
Control0–0 - 31001
SNP9ACase2–1 - 250.0360.1630.005
Control0–7 - 240.2260.21
SNP10GCase2–1 - 250.0360.1630.005
Control0–7 - 240.2260.21
SNP11GCase0–0 - 28001
Control0–0 - 31001
SNP12TCase2–1 - 250.0360.1630.005
Control0–7 - 240.2260.21
SNP13TCase0–3 - 250.1070.1011
Control0–1 - 300.0320.0321
SNP14ACase7–11 - 100.3930.4940.275
Control9–15 - 70.4840.4981
SNP15CCase2–1 - 250.0360.1630.005
Control0–7 - 240.2260.21
SNP16GCase2–1 - 250.0360.1630.005
Control0–7 - 240.2260.21
SNP17CCase0–0 - 28001
Control0–0 - 31001
SNP18GCase7–12 - 90.4290.4970.466
Control5–12 - 140.3870.4580.438
SNP19ACase2–1 - 250.0360.1630.005
Control0–7 - 240.2260.21
SNP20TCase0–0 - 28001
Control0–0 - 31001
indel1Case0–0 - 28001
Control0–0 - 31001
indel2Case2–1 - 250.0360.1630.005
Control0–7 - 240.2260.21
indel3+Case2–4 - 220.1430.2450.066
Control0–8 - 230.2580.2251