Table 5 CTLA4 promoter haplotypes present in cocker spaniels. Number of each haplotype is shown (with frequency in brackets) for cases, 2n = 38, and controls, 2n = 102. NaN: not a number; OR: odds ratio; 95% CI: 95% confidence intervals of the OR. p values for individual 2 × 2 tables are given with significant results coloured red, overall significance p = 0.003
From: Polymorphisms in the CTLA4 promoter sequence are associated with canine hypoadrenocorticism
CTLA4 promoter Haplotype | Cases 2n (%) | Controls 2n (%) | p | OR (95% CI) |
|---|---|---|---|---|
2 | 0 (0%) | 2 (1.96%) | 1.0000 | 0 |
3 | 6 (15.7%) | 4 (3.92%) | 0.0247 | 4.59 (1.21–17.3) |
8 | 27 (71.0%) | 94 (92.1%) | 0.0038 | 0.20 (0.07–0.57) |
11 | 1 (2.63%) | 0 | 0.2714 | NaN |
12 | 4 (10.5%) | 1 (0.98%) | 0.0193 | 11.8 (1.28–110) |
15 | 0 (0%) | 1 (0.98%) | 1.0000 | 0 |