Table 4 Final breed-focused random effects multivariable logistic regression model for risk factors associated with hypothyroidism in dogs under primary veterinary care in the VetCompass Programme in the UK. Clinic attended was included as a random effect

Breed

Crossbreed

Base

 < 0.001

Standard Doberman pinscher

17.02

12.8–22.64

 < 0.001

Tibetan terrier

11.25

8.27–15.32

 < 0.001

Boxer

10.44

8.66–12.58

 < 0.001

Alaskan malamute

9.71

6.11–15.42

 < 0.001

American cocker spaniel

8.64

4.51–16.55

 < 0.001

Shetland sheepdog

8.25

5.38–12.65

 < 0.001

Rhodesian ridgeback

6.80

4.23–10.94

 < 0.001

Irish red setter

5.64

2.96–10.76

 < 0.001

Japanese inu akita

4.69

2.61–8.42

 < 0.001

Dogue de Bordeaux

4.45

2.28–8.7

 < 0.001

Golden retriever

4.36

3.48–5.45

 < 0.001

Beagle

3.08

2.12–4.47

 < 0.001

Miniature schnauzer

3.03

2.19–4.18

 < 0.001

Pomeranian

2.85

1.69–4.81

 < 0.001

Chinese shar-pei

2.80

1.48–5.28

0.001

Siberian husky

2.53

1.64–3.92

 < 0.001

Dalmatian

2.24

1.28–3.92

0.005

Breed not recorded

2.11

0.96–4.64

0.063

English cocker spaniel

2.10

1.7–2.59

 < 0.001

Breed—others

1.86

1.58–2.2

 < 0.001

Border terrier

1.86

1.33–2.59

 < 0.001

Rottweiler

1.64

1.01–2.68

0.047

German shepherd dog

1.51

1.12–2.02

0.006

English springer spaniel

1.43

1.09–1.87

0.010

Labrador retriever

1.40

1.16–1.68

 < 0.001

Toy poodle

1.30

0.64–2.63

0.469

Border collie

1.18

0.9–1.56

0.223

British bulldog

1.10

0.52–2.34

0.801

Labradoodle

1.06

0.56–2

0.859

American bulldog

1.05

0.33–3.27

0.938

Staffordshire bull terrier

0.96

0.76–1.2

0.705

Patterdale terrier

0.90

0.43–1.91

0.786

Sprocker

0.86

0.21–3.48

0.835

Lurcher

0.77

0.4–1.5

0.449

Greyhound

0.77

0.43–1.38

0.384

Maltese

0.67

0.17–2.69

0.571

Whippet

0.58

0.22–1.56

0.281

Bichon frise

0.50

0.27–0.91

0.024

Miniature dachshund

0.49

0.18–1.32

0.159

Cockapoo

0.48

0.15–1.51

0.210

Chihuahua

0.46

0.25–0.84

0.011

Cavalier King Charles spaniel

0.45

0.27–0.75

0.002

Lhasa apso

0.44

0.22–0.85

0.014

West Highland white terrier

0.40

0.26–0.61

 < 0.001

Jack Russell terrier

0.40

0.29–0.54

 < 0.001

Shih-tzu

0.38

0.23–0.64

 < 0.001

Yorkshire terrier

0.38

0.24–0.59

 < 0.001

Pug

0.29

0.09–0.89

0.031

French bulldog

0.27

0.04–1.96

0.197

Cavachon

 ~ 

Cavapoo

 ~ 

Bodyweight relative to breed-sex mean

Below

Base

 < 0.001

At or above

2.06

1.87–2.29

 < 0.001

Uncategorised

0.91

0.78–1.06

0.236

Age (years)

 < 3.0 years

0.02

0.01–0.05

 < 0.001

 < 0.001

3.0—< 5.0 years

0.32

0.25–0.41

 < 0.001

5.0—< 7.0 years

Base

7.0—< 9.0 years

2.12

1.81–2.5

 < 0.001

9.0—< 11.0 years

3.24

2.77–3.79

 < 0.001

11.0—< 13.0 years

4.54

3.86–5.33

 < 0.001

 > or = 13.0 years

5.68

4.8–6.73

 < 0.001

No age available

1.55

0.91–2.64

0.105

Sex-Neuter

Female entire

Base

 < 0.001

Female neutered

1.46

1.26–1.69

 < 0.001

Male entire

1.05

0.89–1.23

0.577

Male neutered

1.31

1.13–1.52

 < 0.001

Unrecorded

1.71

0.73–4.02

0.215

Insurance

Uninsured

Base

 < 0.001

Insured

2.27

2.05–2.52

 < 0.001