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Table 5 Results for risk factors that directly replaced the breed variable in the final breed-focused random effects multivariable logistic regression model (along with age, bodyweight relative to breed-sex mean sex/neuter and insurance status). Adult (> 18 months) bodyweight (kg) replaced the breed and bodyweight relative to breed mean variables in the final breed-focused random effects multivariable logistic regression model. These results report associations between these risk factors and hypothyroidism in dogs under primary veterinary care in the VetCompass Programme in the UK. Clinic attended was included as a random effect

From: Frequency, breed predispositions and other demographic risk factors for diagnosis of hypothyroidism in dogs under primary veterinary care in the UK

Variable

Category

Odds ratio

95% CI*

P-value

Variable P-value

Purebred

Crossbred

Base

  

 < 0.001

Designer

0.84

0.58–1.21

0.342

Purebred

1.49

1.32–1.68

 < 0.001

Kennel Club Recognised Breed

Not recognised

Base

  

 < 0.001

Recognised

1.51

1.35–1.69

 < 0.001

Kennel Club Breed Group

Not Kennel Club recognised breed

Base

  

 < 0.001

Working

6.55

5.64–7.60

 < 0.001

Gundog

1.97

1.72–2.24

 < 0.001

Hound

1.78

1.42–2.22

 < 0.001

Pastoral

1.67

1.40–2.00

 < 0.001

Utility

1.55

1.30–1.84

 < 0.001

Terrier

0.75

0.64–0.88

0.001

Toy

0.53

0.42–0.67

 < 0.001

Skull conformation

Mesocephalic

Base

  

 < 0.001

Dolichocephalic

1.35

1.18–1.55

 < 0.001

Brachycephalic

1.15

1.01–1.31

0.037

Unavailable

0.71

0.63–0.80

 < 0.001

Adult (> 18 months) bodyweight (kg)

 < 10.0

Base

  

 < 0.001

10.0—< 15.0

2.73

2.26–3.30

 < 0.001

15.0—< 20.0

2.95

2.41–3.60

 < 0.001

20.0—< 25.0

3.00

2.46–3.66

 < 0.001

25.0—< 30.0

4.13

3.41–5.01

 < 0.001

30.0—< 40.0

5.60

4.70–6.67

 < 0.001

 ≥ 40.0

9.85

8.10–11.97

 < 0.001

Unavailable

1.82

1.50–2.21

 < 0.001

  1. 95% CI 95% confidence interval