Table 1 Variants detected in canine TLRs by massive sequencing
From: Non-synonymous genetic variation in exonic regions of canine Toll-like receptors
Extracellular TLRs | Intracellular TLRs | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Effect impact | SNP effect | TLR1 | TLR2 | TLR4 | TLR5 | TLR6 | TLR10 | TLR3 | TLR7 | TLR8 | TLR9 | Total |
Low | Syn coding | 2 | 5 | 4 | 28 | 2 | 5 | 6 | 6 | 8 | 7 | 73 |
Moderate | Non-syn coding | 4 | 3 | 12 | 23 | 4 | 3 | 1 | 3 | 4 | 7 | 64 |
Total coding SNP (cSNP) | 6 | 8 | 16 | 51 | 6 | 8 | 7 | 9 | 12 | 14 | 137 | |
Modifier | Downstream | 1 | 4 | 0 | 0 | 2 | 3 | 0 | 0 | 2 | 1 | 12 |
Intron | 0 | 0 | 6 | 3 | 0 | 0 | 10 | 7 | 0 | 2 | 28 | |
Upstream | 0 | 6 | 0 | 0 | 2 | 1 | 1 | 1 | 1 | 0 | 12 | |
UTR 3′ | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 10 | 0 | 0 | 14 | |
Total non coding SNP (ncSNP) | 1 | 10 | 10 | 3 | 4 | 4 | 11 | 18 | 3 | 3 | 66 | |
Total SNP | 7 | 18 | 26 | 54 | 10 | 12 | 18 | 27 | 15 | 17 | 204 | |