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Table 1 Variants detected in canine TLRs by massive sequencing

From: Non-synonymous genetic variation in exonic regions of canine Toll-like receptors

   Extracellular TLRs Intracellular TLRs  
Effect impact SNP effect TLR1 TLR2 TLR4 TLR5 TLR6 TLR10 TLR3 TLR7 TLR8 TLR9 Total
Low Syn coding 2 5 4 28 2 5 6 6 8 7 73
Moderate Non-syn coding 4 3 12 23 4 3 1 3 4 7 64
Total coding SNP (cSNP) 6 8 16 51 6 8 7 9 12 14 137
Modifier Downstream 1 4 0 0 2 3 0 0 2 1 12
  Intron 0 0 6 3 0 0 10 7 0 2 28
  Upstream 0 6 0 0 2 1 1 1 1 0 12
  UTR 3′ 0 0 4 0 0 0 0 10 0 0 14
Total non coding SNP (ncSNP) 1 10 10 3 4 4 11 18 3 3 66
Total SNP 7 18 26 54 10 12 18 27 15 17 204
  1. Variants are classified according to their effect on the protein and their spread along cell surface or intracellular TLRs.