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  1. Research

    Corneal ulcerative disease in dogs under primary veterinary care in England: epidemiology and clinical management

    Corneal ulcerative disease (CUD) has the potential to adversely affect animal welfare by interfering with vision and causing pain. The study aimed to investigate for the first time the prevalence, breed-based ...

    Dan G. O’Neill, Monica M. Lee, Dave C. Brodbelt, David B. Church and Rick F. Sanchez

    Canine Genetics and Epidemiology 2017 4:5

    Published on: 15 June 2017

  2. Research

    Correlation of neuter status and expression of heritable disorders

    Gonadectomy, or neutering, is a very common surgery for dogs having many positive effects on behavior, health, and longevity. There are also certain risks associated with neutering including the development of...

    Janelle M. Belanger, Thomas P. Bellumori, Danika L. Bannasch, Thomas R. Famula and Anita M. Oberbauer

    Canine Genetics and Epidemiology 2017 4:6

    Published on: 26 May 2017

  3. Research

    Genetic mapping of principal components of canine pelvic morphology

    Concentrated breeding effort to produce various body structures and behaviors of dogs to suit human demand has inadvertently produced unwanted traits and diseases that accompany the morphological and behaviora...

    Mark J. Fealey, Joy Li, Rebel J. E. Todhunter, Ursula Krotscheck, Kei Hayashi, Marina J. McConkey, Adam R. Boyko, Jessica J. Hayward and Rory J. Todhunter

    Canine Genetics and Epidemiology 2017 4:4

    Published on: 24 March 2017

  4. Research

    Osteosarcoma inheritance in two families of Scottish deerhounds

    Osteosarcoma is the most common neoplastic disease in Scottish Deerhounds. For Deerhounds, a 2007 population-based study concluded that a single dominant genetic factor largely governed disease risk. For Greyh...

    John E. Dillberger and Sara Ann McAtee

    Canine Genetics and Epidemiology 2017 4:3

    Published on: 17 March 2017

  5. Research

    DNM1 mutation status, sex, and sterilization status of a cohort of Labrador retrievers with and without cranial cruciate ligament rupture

    Exercise-induced collapse (EIC) due to DNM1 mutation and rupture of the cranial cruciate ligament are both common syndromes in the Labrador retriever breed. A cohort of 313 Labradors was recruited based on their ...

    Kari J Ekenstedt, Katie M Minor, Aaron K Rendahl and Michael G Conzemius

    Canine Genetics and Epidemiology 2017 4:2

    Published on: 2 February 2017

  6. Research

    DachsLife 2015: an investigation of lifestyle associations with the risk of intervertebral disc disease in Dachshunds

    Intervertebral disc disease (IVDD) represents a major problem in the Dachshund, with at a relative risk of IVDD 10–12 times higher than other breeds, and an estimated 19–24 % of Dachshunds showing clinical sig...

    R. M. A. Packer, I. J. Seath, D. G. O’Neill, S. De Decker and H. A. Volk

    Canine Genetics and Epidemiology 2016 3:8

    Published on: 5 November 2016

  7. Research

    A genetic assessment of the English bulldog

    This study examines genetic diversity among 102 registered English Bulldogs used for breeding based on maternal and paternal haplotypes, allele frequencies in 33 highly polymorphic short tandem repeat (STR) lo...

    Niels C. Pedersen, Ashley S. Pooch and Hongwei Liu

    Canine Genetics and Epidemiology 2016 3:6

    Published on: 29 July 2016

  8. Research

    A large deletion in RPGR causes XLPRA in Weimaraner dogs

    Progressive retinal atrophy (PRA) belongs to a group of inherited retinal disorders associated with gradual vision impairment due to degeneration of retinal photoreceptors in various dog breeds. PRA is highly ...

    Regina Kropatsch, Denis A. Akkad, Matthias Frank, Carsten Rosenhagen, Janine Altmüller, Peter Nürnberg, Jörg T. Epplen and Gabriele Dekomien

    Canine Genetics and Epidemiology 2016 3:7

    Published on: 8 July 2016

  9. Research

    Demography and health of Pugs under primary veterinary care in England

    The Pug is an ancient dog breed and was the fifth most commonly registered UK pedigree breed in 2014. However, the breed has been reported to be predisposed to several disorders including ocular, respiratory a...

    Dan G. O’Neill, Elisabeth C. Darwent, David B. Church and Dave C. Brodbelt

    Canine Genetics and Epidemiology 2016 3:5

    Published on: 10 June 2016

  10. Research

    Protein expression and genetic variability of canine Can f 1 in golden and Labrador retriever service dogs

    Valued for trainability in diverse tasks, dogs are the primary service animal used to assist individuals with disabilities. Despite their utility, many people in need of service dogs are sensitive to the prima...

    Christina Breitenbuecher, Janelle M. Belanger, Kerinne Levy, Paul Mundell, Valerie Fates, Liza Gershony, Thomas R. Famula and Anita M. Oberbauer

    Canine Genetics and Epidemiology 2016 3:3

    Published on: 22 April 2016

  11. Research

    Trends in popularity of some morphological traits of purebred dogs in Australia

    The morphology of dogs can provide information about their predisposition to some disorders. For example, larger breeds are predisposed to hip dysplasia and many neoplastic diseases. Therefore, longitudinal tr...

    Kendy T. Teng, Paul D. McGreevy, Jenny-Ann L. M. L. Toribio and Navneet K. Dhand

    Canine Genetics and Epidemiology 2016 3:2

    Published on: 5 April 2016

  12. Research

    Prevalence of pectinate ligament dysplasia and associations with age, sex and intraocular pressure in the Basset hound, Flatcoated retriever and Dandie Dinmont terrier

    The aims of this study were to: determine the prevalence of pectinate ligament dysplasia (PLD) in populations of Basset hounds (BH), Flatcoated retrievers (FCR) and Dandie Dinmont terriers (DDT) resident in th...

    James A. C. Oliver, Abel Ekiri and Cathryn S. Mellersh

    Canine Genetics and Epidemiology 2016 3:1

    Published on: 12 March 2016

  13. Research

    A search for genetic diversity among Italian Greyhounds from Continental Europe and the USA and the effect of inbreeding on susceptibility to autoimmune disease

    Previous studies documented the problem of inbreeding among Italian Greyhounds (IG) from the USA and its possible role in a multiple autoimmune disease syndrome. The present study is an extension of these earl...

    Niels C. Pedersen, Hongwei Liu, Angela Leonard and Layle Griffioen

    Canine Genetics and Epidemiology 2015 2:17

    Published on: 30 October 2015

  14. Research

    Evaluation of whole-genome sequencing of four Chinese crested dogs for variant detection using the ion proton system

    Next generation sequencing (NGS) has traditionally been performed by large genome centers, but in recent years, the costs for whole-genome sequencing (WGS) have decreased substantially. With the introduction o...

    Agnese Viluma, Shumaila Sayyab, Sofia Mikko, Göran Andersson and Tomas F. Bergström

    Canine Genetics and Epidemiology 2015 2:16

    Published on: 8 October 2015

  15. Research

    The effect of genetic bottlenecks and inbreeding on the incidence of two major autoimmune diseases in standard poodles, sebaceous adenitis and Addison’s disease

    Sebaceous adenitis (SA) and Addison’s disease (AD) increased rapidly in incidence among Standard Poodles after the mid-twentieth century. Previous attempts to identify specific genetic causes using genome wide...

    Niels C. Pedersen, Lynn Brucker, Natalie Green Tessier, Hongwei Liu, Maria Cecilia T. Penedo, Shayne Hughes, Anita Oberbauer and Ben Sacks

    Canine Genetics and Epidemiology 2015 2:14

    Published on: 27 August 2015

  16. Research

    Genetics and epidemiology of hypothyroidism and symmetrical onychomadesis in the Gordon setter and the English setter

    Hypothyroidism is one of the most common endocrine disorders, whereas symmetrical onychomadesis is a rare claw disease in the general dog population. The aims of this study were to estimate the prevalence of h...

    Martine Lund Ziener, Stina Dahlgren, Stein Istre Thoresen and Frode Lingaas

    Canine Genetics and Epidemiology 2015 2:12

    Published on: 21 August 2015

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