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  1. Content type: Research

    Despite its Gallic name, the French Bulldog is a breed of both British and French origin that was first recognised by The Kennel Club in 1906. The French Bulldog has demonstrated recent rapid rises in Kennel C...

    Authors: Dan G. O’Neill, Lauren Baral, David B. Church, Dave C. Brodbelt and Rowena M. A. Packer

    Citation: Canine Genetics and Epidemiology 2018 5:3

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  2. Content type: Research

    Canine DNA-testing has become an important tool in purebred dog breeding and many breeders use genetic testing results when planning their breeding strategies. In addition, information obtained from testing of...

    Authors: Saija Ahonen, Ian Seath, Clare Rusbridge, Susan Holt, Gill Key, Travis Wang, Peixiang Wang and Berge A. Minassian

    Citation: Canine Genetics and Epidemiology 2018 5:2

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  3. Content type: Research

    The selection of a future breeding dog is a complicated task, in which disease characteristics and different traits have to be combined and weighed against one another. Truncation selection, that is the exclus...

    Authors: Katrien Wijnrocx, Liesbeth François, Peter Goos, Nadine Buys and Steven Janssens

    Citation: Canine Genetics and Epidemiology 2018 5:1

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  4. Content type: Research

    Breed-related health problems in dogs have received increased focus over the last decade. Responsibility for causing and/or solving these problems has been variously directed towards dog breeders and kennel cl...

    Authors: Dan G. O’Neill, Sylvia F. A. Keijser, Åke Hedhammar, Caroline Kisko, Gregoire Leroy, Aimée Llewellyn-Zaidi, Sofia Malm, Patricia N. Olson, Rowena M. A. Packer, Jean Francois Rousselot, Ian J. Seath, Jason W. Stull and Brenda N. Bonnett

    Citation: Canine Genetics and Epidemiology 2017 4:16

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  5. Content type: Research

    The Border Terrier is a working terrier type that is generally considered to be a relatively healthy and hardy breed. This study aimed to characterise the demography and common disorders of Border Terriers rec...

    Authors: Dan G. O’Neill, Elisabeth C. Darwent, David B. Church and Dave C. Brodbelt

    Citation: Canine Genetics and Epidemiology 2017 4:15

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  6. Content type: Research

    Pure breeding of dogs has led to over 700 heritable disorders, of which almost 300 are Mendelian in nature. Seventy percent of the characterized mutations have an autosomal recessive mode of inheritance, indic...

    Authors: Niels C. Pedersen, Bonnie Shope and Hongwei Liu

    Citation: Canine Genetics and Epidemiology 2017 4:11

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    The Letter to the Editor to this article has been published in Canine Genetics and Epidemiology 2018 5:4

  7. Content type: Research

    Rottweilers are reportedly predisposed to many disorders but accurate prevalence information relating to the general population are lacking. This study aimed to describe demography, mortality and commonly reco...

    Authors: Dan G. O’Neill, Wee Yin Seah, David B. Church and Dave C. Brodbelt

    Citation: Canine Genetics and Epidemiology 2017 4:13

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  8. Content type: Research

    Studying cancer and other diseases poses a problem due to their protracted and multifactorial nature. Prospective studies are useful to investigate chronic disease processes since collection of lifestyle infor...

    Authors: Melissa Simpson, Erin Searfoss, Sharon Albright, Diane E. Brown, Barbara Wolfe, Nancy K. Clark, Susan E. McCann, David Haworth, Mike Guy and Rod Page

    Citation: Canine Genetics and Epidemiology 2017 4:14

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  9. Content type: Research

    Canine lumbosacral stenosis is defined as narrowing of the caudal lumbar and/or sacral vertebral canal. A risk factor for neurologic problems in many large sized breeds, lumbosacral stenosis can also cause ear...

    Authors: Meenakshi Mukherjee, Jeryl C. Jones and Jianbo Yao

    Citation: Canine Genetics and Epidemiology 2017 4:12

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  10. Content type: Research

    Genetic polymorphisms within the glutathione S-transferase P1 (GSTP1) gene affect the elimination of toxic xenobiotics by the GSTP1 enzyme. In dogs, exposure to environmental chemicals that may be GSTP1 substrate...

    Authors: James Sacco, Sarah Mann and Keller Toral

    Citation: Canine Genetics and Epidemiology 2017 4:9

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  11. Content type: Research

    Pedigree or purebred dogs are often stated to have high prevalence of disorders which are commonly assumed to be a consequence of inbreeding and selection for exaggerated features. However, few studies empiric...

    Authors: B. M. Wiles, A. M. Llewellyn-Zaidi, K.M. Evans, D. G. O’Neill and T. W. Lewis

    Citation: Canine Genetics and Epidemiology 2017 4:8

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  12. Content type: Research

    The German Shepherd Dog (GSD) has been widely used for a variety of working roles. However, concerns for the health and welfare of the GSD have been widely aired and there is evidence that breed numbers are no...

    Authors: Dan G. O’Neill, Noel R. Coulson, David B. Church and Dave C. Brodbelt

    Citation: Canine Genetics and Epidemiology 2017 4:7

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  13. Content type: Research

    Corneal ulcerative disease (CUD) has the potential to adversely affect animal welfare by interfering with vision and causing pain. The study aimed to investigate for the first time the prevalence, breed-based ...

    Authors: Dan G. O’Neill, Monica M. Lee, Dave C. Brodbelt, David B. Church and Rick F. Sanchez

    Citation: Canine Genetics and Epidemiology 2017 4:5

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  14. Content type: Research

    Gonadectomy, or neutering, is a very common surgery for dogs having many positive effects on behavior, health, and longevity. There are also certain risks associated with neutering including the development of...

    Authors: Janelle M. Belanger, Thomas P. Bellumori, Danika L. Bannasch, Thomas R. Famula and Anita M. Oberbauer

    Citation: Canine Genetics and Epidemiology 2017 4:6

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  15. Content type: Research

    Concentrated breeding effort to produce various body structures and behaviors of dogs to suit human demand has inadvertently produced unwanted traits and diseases that accompany the morphological and behaviora...

    Authors: Mark J. Fealey, Joy Li, Rebel J. E. Todhunter, Ursula Krotscheck, Kei Hayashi, Marina J. McConkey, Adam R. Boyko, Jessica J. Hayward and Rory J. Todhunter

    Citation: Canine Genetics and Epidemiology 2017 4:4

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  16. Content type: Research

    Osteosarcoma is the most common neoplastic disease in Scottish Deerhounds. For Deerhounds, a 2007 population-based study concluded that a single dominant genetic factor largely governed disease risk. For Greyh...

    Authors: John E. Dillberger and Sara Ann McAtee

    Citation: Canine Genetics and Epidemiology 2017 4:3

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  17. Content type: Research

    Exercise-induced collapse (EIC) due to DNM1 mutation and rupture of the cranial cruciate ligament are both common syndromes in the Labrador retriever breed. A cohort of 313 Labradors was recruited based on their ...

    Authors: Kari J Ekenstedt, Katie M Minor, Aaron K Rendahl and Michael G Conzemius

    Citation: Canine Genetics and Epidemiology 2017 4:2

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  18. Content type: Research

    In humans, reduced activity of the enzyme monoamine oxidase type A (MAOA) due to genetic polymorphisms within the MAOA gene leads to increased brain neurotransmitter levels associated with aggression. In order to...

    Authors: James Sacco, Andrew Ruplin, Paul Skonieczny and Michael Ohman

    Citation: Canine Genetics and Epidemiology 2017 4:1

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  19. Content type: Research

    Despite decades of studying, the mechanisms maintaining high diversity in the genes of the Major Histocompatibility Complex (MHC) are still puzzling scientists. In addition to pathogen recognition and other fu...

    Authors: Alina K. Niskanen, Lorna J. Kennedy, Hannes Lohi, Jouni Aspi and Tanja Pyhäjärvi

    Citation: Canine Genetics and Epidemiology 2016 3:9

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  20. Content type: Research

    Intervertebral disc disease (IVDD) represents a major problem in the Dachshund, with at a relative risk of IVDD 10–12 times higher than other breeds, and an estimated 19–24 % of Dachshunds showing clinical sig...

    Authors: R. M. A. Packer, I. J. Seath, D. G. O’Neill, S. De Decker and H. A. Volk

    Citation: Canine Genetics and Epidemiology 2016 3:8

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  21. Content type: Research

    This study examines genetic diversity among 102 registered English Bulldogs used for breeding based on maternal and paternal haplotypes, allele frequencies in 33 highly polymorphic short tandem repeat (STR) lo...

    Authors: Niels C. Pedersen, Ashley S. Pooch and Hongwei Liu

    Citation: Canine Genetics and Epidemiology 2016 3:6

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  22. Content type: Research

    Progressive retinal atrophy (PRA) belongs to a group of inherited retinal disorders associated with gradual vision impairment due to degeneration of retinal photoreceptors in various dog breeds. PRA is highly ...

    Authors: Regina Kropatsch, Denis A. Akkad, Matthias Frank, Carsten Rosenhagen, Janine Altmüller, Peter Nürnberg, Jörg T. Epplen and Gabriele Dekomien

    Citation: Canine Genetics and Epidemiology 2016 3:7

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  23. Content type: Research

    The Pug is an ancient dog breed and was the fifth most commonly registered UK pedigree breed in 2014. However, the breed has been reported to be predisposed to several disorders including ocular, respiratory a...

    Authors: Dan G. O’Neill, Elisabeth C. Darwent, David B. Church and Dave C. Brodbelt

    Citation: Canine Genetics and Epidemiology 2016 3:5

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    66 days from submission to first decision
    21 days from acceptance to publication

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