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Table 4 DLA-haplotypes and alleles associated with hypothyroidism or protection against hypothyroidism in the Gordon setter

From: Genetics and epidemiology of hypothyroidism and symmetrical onychomadesis in the Gordon setter and the English setter

  Total Cases Controls Cases/controls
DLA-haplotype or allele % n = 322 % n = 136 % n = 186 OR 95 % CI p-value
DRB1*00103/DQA1*00101/DQB1*00201 8.3 27 14.7 20 3.7 7 4.4 1.8 - 11.5 0.0005
DLA-DQB1*00201 21.4 69 33.8 46 12.4 23 3.6 2.1 - 6.4 0.000005
DRB1*04901/DQA1*01001/DQB1*01901 18.9 61 25.7 35 13.9 26 2.1 1.2 - 3.7 0.008
DRB1*00101/DQA1*00101/DQB1*00201 11.1 36 15.4 21 8.0 15 2.1 1.0 - 4.3 0.04
DRB1*01801/DQA1*00101/DQB1*00802 31.9 103 18.3 25 41.9 78 0.3 0.2 - 0.5 0.000006
DRB1*01501/DQA1*00601/DQB1*02301 5.9 19 2.2 3 8.6 16 0.2 0.1 - 0.8 0.001