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Table 1 Characteristics of five canine UC cell lines

From: A cultured approach to canine urothelial carcinoma: molecular characterization of five cell lines

Cell Line ID

Initial passage

Breed

Sex

Average chromosome #

Specific structural changes

K9TCC-PU-An (TCC2)

p3

Scottish Terrier

FS

131.6

TD(10,36), t(36;38),f(13;13)

K9TCC-PU-In (TCC6)

p1

German Shepherd

FS

103.3

TD(10,36), f(13;13)

K9TCC-PU-Mx (TCC5)

p5

German Shepherd

FS

134.6

TD(10,36)

K9TCC-PU-Sh (TCC4)

p6

Collie

FS

105.5

TD(36,38), t(36;38),

K9TCC (TCC3)

p14

Mixed Breed

FS

76.2

TD(10)

  1. Five cell lines, derived from primary biopsy specimens, were evaluated in this study. Cell line identifier, initial passage number, breed, and sex (FS female spayed) are shown. Chromosomes from metaphase spreads (n = 30) of each cell line were counted to determine an average chromosome number. Recurrent structural changes identified by FISH evaluation are shown (TD tandem duplication, t translocation, f fusion)