Fig. 4

Distribution of von Willebrand type I symptoms in correlation with the corresponding genotype. Percentages of dogs with (symptomatic) or without symptoms (asymptomatic) were determined for each genotype group. 23.2% of heterozygotes (WT/MUT) showed bleeding symptoms compared to 45.5% of homozygous dogs (MUT/MUT). No symptoms were reported for wild-type (WT/WT) dogs without the mutation. Based on these results, hereditary of vWDI in Kromfohrländer seems to follow an autosomal dominant inheritance with an incomplete penetrance