Table 1 Descriptive and univariable logistic regression results for breed as a risk factor for osteosarcoma during 2016 in dogs under primary veterinary care in the VetCompass Programme in the UK. Column percentages shown in brackets. ^aCI confidence interval

Crossbreed

62 (18.73)

194,429 (21.48)

Base

 < 0.001

Scottish Deerhound

4 (1.21)

118 (0.01)

106.30

38.06–296.90

 < 0.001

Leonberger

4 (1.21)

266 (0.03)

47.16

17.03–130.54

 < 0.001

Great Dane

11 (3.32)

1258 (0.14)

27.42

14.41–52.19

 < 0.001

Rottweiler

61 (18.43)

7223 (0.80)

26.48

18.58–37.74

 < 0.001

Greyhound

34 (10.27)

5422 (0.60)

19.66

12.93–29.90

 < 0.001

Old English Sheepdog

3 (0.91)

734 (0.08)

12.82

4.01–40.92

 < 0.001

Bull Mastiff

4 (1.21)

1620 (0.18)

7.74

2.81–21.31

 < 0.001

German Pointer

4 (1.21)

1921 (0.21)

6.53

2.37–17.97

 < 0.001

Standard Doberman Pinscher

5 (1.51)

2456 (0.27)

6.38

2.56–15.89

 < 0.001

Lurcher

6 (1.81)

6016 (0.66)

3.13

1.35–7.23

0.008

Golden Retriever

8 (2.42)

9785 (1.08)

2.56

1.23–5.36

0.012

Labrador Retriever

38 (11.48)

59,925 (6.62)

1.99

1.33–2.98

0.001

Boxer

6 (1.81)

9438 (1.04)

1.99

0.86–4.61

0.107

German Shepherd Dog

11 (3.32)

21,360 (2.36)

1.61

0.85–3.07

0.143

English Springer Spaniel

10 (3.02)

20,198 (2.23)

1.55

0.80–3.03

0.197

Labradoodle

2 (0.60)

7483 (0.83)

0.84

0.20–3.43

0.806

English Bulldog

2 (0.60)

8407 (0.93)

0.75

0.18–3.05

0.683

Husky

2 (0.60)

8563 (0.95)

0.73

0.18–2.99

0.665

Breed type—Others

30 (9.06)

136,328 (15.06)

0.69

0.45–1.07

0.095

Staffordshire Bull Terrier

11 (3.32)

53,045 (5.86)

0.65

0.34–1.23

0.188

West Highland White Terrier

3 (0.91)

18,875 (2.09)

0.50

0.16–1.59

0.239

Beagle

1 (0.30)

8069 (0.89)

0.39

0.05–2.80

0.348

Border Collie

2 (0.60)

24,388 (2.69)

0.26

0.06–1.05

0.059

Yorkshire Terrier

2 (0.60)

28,178 (3.11)

0.22

0.05–0.91

0.037

English Cocker Spaniel

2 (0.60)

33,075 (3.65)

0.19

0.05–0.78

0.021

Pug

1 (0.30)

16,213 (1.79)

0.19

0.03–1.39

0.103

Shih-tzu

1 (0.30)

32,909 (3.64)

0.10

0.01–0.69

0.020

Jack Russell Terrier

1 (0.30)

48,569 (5.37)

0.06

0.01–0.47

0.007

Bichon Frise

0 (0.00)

13,269 (1.47)

 ~ 

Border Terrier

0 (0.00)

9651 (1.07)

 ~ 

Cavalier King Charles Spaniel

0 (0.00)

17,258 (1.91)

 ~ 

Chihuahua

0 (0.00)

36,794 (4.06)

 ~ 

Cockapoo

0 (0.00)

18,404 (2.03)

 ~ 

French Bulldog

0 (0.00)

16,397 (1.81)

 ~ 

Lhasa Apso

0 (0.00)

12,549 (1.39)

 ~ 

Miniature Schnauzer

0 (0.00)

8397 (0.93)

 ~ 

Pomeranian

0 (0.00)

6221 (0.69)

 ~