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Table 2 Descriptive and univariable logistic regression results for breed-derived risk factors for osteosarcoma during 2016 in dogs under primary veterinary care in the VetCompass Programme in the UK. Column percentages shown in brackets. aCI confidence interval

From: Dog breeds and conformations predisposed to osteosarcoma in the UK: a VetCompass study

Variable

Category

Case No. (%)

Non-case No. (%)

Odds ratio

95% CIa

Category P-value

Variable P-value

Breed purity

Crossbred

62 (18.73)

194,429 (21.56)

Base

  

0.003

Designer

8 (2.42)

52,863 (5.86)

0.47

0.23–0.99

0.047

 

Purebred

261 (78.85)

654,647 (72.58)

1.25

0.95–1.65

0.114

 

Kennel Club Recognised Breed

Not recognised

75 (22.66)

262,287 (29.08)

Base

  

0.008

Recognised

256 (77.34)

639,652 (70.92)

1.40

1.08–1.81

0.010

 

Kennel Club Breed Group

Not Kennel Club recognised breed

75 (22.66)

262,287 (29.08)

Base

  

 < 0.001

Terrier

15 (4.53)

145,912 (16.18)

0.36

0.21–0.63

 < 0.001

 

Gundog

66 (19.94)

135,607 (15.04)

1.70

1.22–2.37

0.002

 

Working

102 (30.82)

39,114 (4.34)

9.12

6.77–12.29

 < 0.001

 

Pastoral

19 (5.74)

52,964 (5.87)

1.25

0.76–2.08

0.377

 

Utility

8 (2.42)

102,655 (11.38)

0.27

0.13–0.56

 < 0.001

 

Hound

42 (12.69)

31,376 (3.48)

4.68

3.21–6.83

 < 0.001

 

Toy

4 (1.21)

132,024 (14.64)

0.11

0.04–0.29

 < 0.001

 

Chondrodystrophy

Non chondrodystrophic

238 (71.90)

309,279 (34.17)

Base

  

 < 0.001

Chondrodystrophic

23 (6.95)

345,327 (38.15)

0.09

0.06–0.13

 < 0.001

 

Uncategorised

70 (21.15)

250,605 (27.68)

0.36

0.27–0.47

 < 0.001

 

Skull conformation

Mesocephalic

169 (51.06)

417,452 (46.12)

Base

  

 < 0.001

Brachycephalic

20 (6.04)

167,413 (18.49)

0.30

0.19–0.47

 < 0.001

 

Dolichocephalic

72 (21.75)

69,782 (7.71)

2.55

1.93–3.36

 < 0.001

 

Uncategorised

70 (21.15)

250,564 (27.68)

0.69

0.52–0.91

0.009

 

Haircoat length

Medium

44 (13.29)

191,904 (21.20)

Base

  

 < 0.001

Short

210 (63.44)

339,558 (37.51)

2.70

1.95–3.73

 < 0.001

 

Long

7 (2.11)

92.018 (10.17)

0.33

0.15–0.74

0.007

 

Uncategorised

70 (21.15)

281,731 (31.12)

1.08

0.74–1.58

0.676

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