Table 3 Descriptive and univariable logistic regression results for non-breed-related demographic risk factors evaluated for osteosarcoma during 2016 in dogs under primary veterinary care in the VetCompass Programme in the UK. Column percentages shown in brackets. ^aCI confidence interval

Adult (> 18 months) bodyweight (kg)

 < 10.0

4 (1.21)

213,321 (23.57)

0.13

0.05–0.38

 < 0.001

10.0—< 20.0

24 (7.25)

167,774 (18.53)

Base

 < 0.001

20.0—< 30.0

64 (19.34)

117,620 (12.99)

3.80

2.38–6.08

 < 0.001

30.0—< 40.0

78 (23.56)

69,856 (7.72)

7.81

4.94–12.33

 < 0.001

40.0—< 50.0

48 (14.50)

19,813 (2.19)

16.94

10.37–27.65

 < 0.001

50.0—< 60.0

25 (7.55)

4,452 (0.49)

39.26

22.40–68.78

 < 0.001

 ≥ 60.0

8 (2.42)

1,913 (0.21)

29.23

13.12–65.15

 < 0.001

Uncategorised

80 (24.17)

310,462 (34.30)

1.80

1.14–2.84

0.011

Bodyweight relative to breed mean

Lower

91 (27.49)

317,257 (35.05)

Base

 < 0.001

Equal/Higher

160 (48.34)

275,353 (30.42)

2.03

1.57–2.62

 < 0.001

Uncategorised

80 (24.17)

312,601 (34.53)

0.89

0.66–1.20

0.457

Age (years)

 < 4.0

8 (2.42)

412,142 (45.53)

0.14

0.06–0.31

 < 0.001

4.0—< 6.0

20 (6.04)

139,739 (15.44)

Base

 < 0.001

6.0—< 8.0

56 (16.92)

113,515 (12.54)

3.45

2.07–5.74

 < 0.001

8.0—< 10.0

101 (30.51)

90,840 (10.04)

7.77

4.81–12.55

 < 0.001

10.0—< 12.0

83 (25.08)

66,450 (7.34)

8.73

5.36–14.22

 < 0.001

12.0—< 14.0

40 (12.08)

41,950 (4.63)

6.66

3.89–11.40

 < 0.001

 ≥ 14.0

22 (6.65)

28,152 (3.11)

5.46

2.98–10.01

 < 0.001

Uncategorised

1 (0.30)

12,423 (1.37)

0.56

0.08–4.19

0.574

Sex-neuter

Female entire

54 (16.31)

233,772 (25.83)

Base

 < 0.001

Female neutered

113 (34.14)

197,768 (21.85)

2.47

1.79–3.42

 < 0.001

Male entire

62 (18.73)

259,460 (28.66)

1.03

0.72–1.49

0.856

Male neutered

102 (30.82)

209,982 (23.20)

2.10

1.51–2.92

 < 0.001

Uncategorised

0 (0.00)

4,229 (0.47)

 ~ 

Insurance

Non-insured

252 (76.13)

787,723 (87.02)

Base

 < 0.001

Insured

79 (23.87)

117,488 (12.98)

2.10

1.63–2.71

 < 0.001

Vet group

A

2 (0.60)

3,913 (0.43)

1.57

0.39–6.35

B

81 (24.47)

297,571 (32.87)

0.84

0.63–1.10

C

24 (7.25)

40,576 (4.48)

1.82

1.18–2.81

D

92 (27.79)

157,387 (17.39)

1.80

1.38–2.35

E

132 (39.88)

405,764 (44.83)

Base

 < 0.001