Fig. 1
From: Genomic analysis and prediction of genomic values for distichiasis in Staffordshire bull terriers
Mixed linear model association analysis. A: A Manhattan plot displaying the MLMA performed in GCTA. The association analysis was based on 94,697 SNP markers and 731 dogs (324 cases and 407 controls). The significance level (blue line) was set to 1.24 × 10–05 using Bonferroni correction to adjust for multiple testing considering the LD, haploblock structure and number of independent SNPs after pruning the data. A second significance level (red line) was set to 5.28 × 10–07, using Bonferroni correction to adjust for all markers in the data. B: A quantile–quantile (q-q) plot showing the expected p value against the observed p-values of the MLMA