Genomic analysis and prediction of genomic values for distichiasis in Staffordshire bull terriers

Table 1 The top four associated SNPs

Chr	SNP	BP position	Risk allele /Protective allele	Risk allele frequency affected	Risk allele frequency unaffected	OR	95% CI	P-value (MLMA)	Absolute effect size (BayesR)
1	BICF2P714726	73,777,342	G /A	0.94	0.85	2.66	1.84—3.85	1.90 × 10^–06	0.017
18	BICF2P1386405	27,949,474	T/C	0.34	0.20	2.03	1.60—2.57	9.42 × 10^–06	0.007
32	BICF2G630590287	17,605,832	T/C	0.33	0.21	1.84	1.46—2.33	1.21 × 10^–05	0.003
34	BICF2S232639	14,960,862	G/A	0.54	0.38	1.92	1.55—2.36	6.77 × 10^–06	0.010

The four top SNPs identified in the association analysis in the MLMA in GCTA, and with the effect size from BayesR. The base pair position is given in can.fam4 reference genome. The association study was based on 731 phenotyped SBTs (407 controls and 324 cases), and 94,697 autosomal SNP markers

ISSN: 2662-9380