The Kennel Club. Breed Information Centre. http://www.thekennelclub.org.uk/services/public/breed/. Accessed 16 Oct 2017.
Holowinski M. The everything Rottweiler book: a complete guide to raising, training, and caring for your Rottweiler. Avon: Adams Media; 2004. p. 287.
Biniok J. Our Best Friends: The Rottweiler. Eldorado Ink: Stockton; 2010. p. 112.
American Kennel Club. Dog Breeds: This is the official list of all American Kennel Club dog breeds. http://www.akc.org/breeds/index.cfm. Accessed 16 Oct 2017.
The Kennel Club. Breed registration statistics. http://www.thekennelclub.org.uk/registration/breed-registration-statistics/. Accessed 16 Oct 2017.
Gough A, Thomas A. Breed predispositions to disease in dogs and cats. 2nd ed. Chicester: Wiley-Blackwell; 2010.
Taylor-Brown FE, Meeson RL, Brodbelt DC, Church DB, McGreevy PD, Thomson PC, et al. Epidemiology of cranial cruciate ligament disease diagnosis in dogs attending primary-care veterinary practices in England. Vet Surg. 2015;44(6):777–83.
LaFond E, Breur GJ, Austin CC. Breed susceptibility for developmental orthopedic diseases in dogs. J Am Vet Med Assoc. 2002;38(5):467–77.
Rosenberger JA, Pablo NV, Crawford PC. Prevalence of and intrinsic risk factors for appendicular osteosarcoma in dogs: 179 cases (1996–2005). J Am Vet Med Assoc. 2007;231(7):1076–80.
Borgarelli M, Santilli RA, Chiavegato D, D’Agnolo G, Zanatta R, Mannelli A, et al. Prognostic indicators for dogs with dilated cardiomyopathy. J Vet Intern Med. 2006;20(1):104–10.
Goddard A, Leisewitz AL. Canine parvovirus. Vet Clin N Am Small Anim Pract. 2010;40(6):1041–53.
Jagielski D, Lechowski R, Hoffmann-Jagielska M, Winiarczyk S. A retrospective study of the incidence and prognostic factors of multicentric lymphoma in dogs (1998–2000). J Veterinary Med Ser A. 2002;49(8):419–24.
Schultz RM, Puchalski SM, Kent M, Moore PF. Skeletal lesions of histiocytic sarcoma in nineteen dogs. Vet Radiol Ultrasound. 2007;48(6):539–43.
Egenvall A, Hagman R, Bonnett BN, Hedhammar A, Olson P, Lagerstedt A-S. Breed risk of pyometra in insured dogs in Sweden. J Vet Intern Med. 2001;15(6):530–8.
Bateson P. Independent inquiry into dog breeding. Cambridge: University of Cambridge; 2010.
Collins LM, Asher L, Summers JF, Diesel G, McGreevy PD. Welfare epidemiology as a tool to assess the welfare impact of inherited defects on the pedigree dog population. Anim Welf. 2010;19:67–75.
Lund JD, Agger JF, Vestergaard KS. Reported behaviour problems in pet dogs in Denmark: age distribution and influence of breed and gender. Prev Vet Med. 1996;28(1):33–48.
Bollen KS, Horowitz J. Behavioral evaluation and demographic information in the assessment of aggressiveness in shelter dogs. Appl Anim Behav Sci. 2008;112(1–2):120–35.
Overall KL, Love M. Dog bites to humans—demography, epidemiology, injury, and risk. J Am Vet Med Assoc. 2001;218(12):1923–34.
Sacks JJ, Sinclair L, Gilchrist J, Golab GC, Lockwood R. Breeds of dogs involved in fatal human attacks in the United States between 1979 and 1998. J Am Vet Med Assoc. 2000;217(6):836–40.
Duffy DL, Hsu Y, Serpell JA. Breed differences in canine aggression. Appl Anim Behav Sci. 2008;114(3–4):441–60.
Fatjo J, Amat M, Mariotti VM, de la Torre JLR, Manteca X. Analysis of 1040 cases of canine aggression in a referral practice in Spain. J Vet Behav Clin App Res. 2007;2(5):158–65.
Wells DL, Morrison DJ, Hepper PG. The effect of priming on perceptions of dog breed traits. Anthrozoös. 2012;25(3):369–77.
Sanchis-Mora S, Pelligand L, Thomas CL, Volk HA, Abeyesinghe SM, Brodbelt DC, et al. Dogs attending primary-care practice in England with clinical signs suggestive of Chiari-like malformation/syringomyelia. Vet Rec. 2016;179(17):436.
Summers J, O’Neill D, Church D, Thomson P, McGreevy P, Brodbelt D. Prevalence of disorders recorded in cavalier king Charles spaniels attending primary-care veterinary practices in England. Canine Genet Epidemiol. 2015;2(1):4.
O’Neill DG, Darwent EC, Church DB, Brodbelt DC. Demography and health of pugs under primary veterinary care in England. Canine Genet Epidemiol. 2016;3(1):1–12.
O’Neill D, Church D, McGreevy P, Thomson P, Brodbelt D. Approaches to canine health surveillance. Canine Genet Epidemiol. 2014;1(1):2.
VetCompass. VetCompass: Health surveillance for UK companion animals. http://www.rvc.ac.uk/VetCOMPASS/. Accessed 16 Oct 2017.
The VeNom Coding Group. VeNom Veterinary Nomenclature. http://www.venomcoding.org. Accessed 16 Oct 2017.
Pearce N. Classification of epidemiological study designs. Int J Epidemiol. 2012;41(2):393–7.
Epi Info 7 CDC. Centers for Disease Control and Prevention (US): Introducing Epi Info 7. http://wwwn.cdc.gov/epiinfo/7. Accessed 16 Oct 2017.
O’Neill DG, Church DB, McGreevy PD, Thomson PC, Brodbelt DC. Prevalence of disorders recorded in dogs attending primary-care veterinary practices in England. PLoS One. 2014;9(3):1–16.
Kirkwood BR, Sterne JAC. Essential medical statistics. 2nd ed. Oxford: Blackwell Science; 2003.
Agresti A, Coull BA. Approximate is better than “exact” for interval estimation of binomial proportions. Am Stat. 1998;52(2):119–26.
McGreevy PD, Nicholas FW. Some practical solutions to welfare problems in dog breeding. Anim Welf. 1999;8:329–41.
O’Neill DG, Meeson RL, Sheridan A, Church DB, Brodbelt DC. The epidemiology of patellar luxation in dogs attending primary-care veterinary practices in England. Canine Genet Epidemiol. 2016;3(1):1–12.
Bartlett PC, Van Buren JW, Neterer M, Zhou C. Disease surveillance and referral bias in the veterinary medical database. Prev Vet Med. 2010;94(3–4):264–71.
Pearce N, Checkoway H, Kriebel D. Bias in occupational epidemiology studies. Occup Environ Med. 2007;64(8):562–8.
Australian National Kennel Council. ANKC National Registration Statistics. http://ankc.org.au/AboutUs/?id=1206. Accessed 16 Oct 2017.
Sandøe P, Kondrup SV, Bennett PC, Forkman B, Meyer I, Proschowsky HF, et al. Why do people buy dogs with potential welfare problems related to extreme conformation and inherited disease? A representative study of Danish owners of four small dog breeds. PLoS One. 2017;12(2):e0172091.
Packer R, Murphy D, Farnworth M. Purchasing popular purebreds: investigating the influence of breed-type on the pre-purchase motivations and behaviour of dog owners. Anim Welf. 2017;26:191–201.
O’Neill DG, Church DB, McGreevy PD, Thomson PC, Brodbelt DC. Longevity and mortality of owned dogs in England. Vet J. 2013;198(3):638–43.
Proschowsky HF, Rugbjerg H, Ersbøll AK. Mortality of purebred and mixed-breed dogs in Denmark. Prev Vet Med. 2003;58(1–2):63–74.
Craig L. Cause of death in dogs according to breed: a necropsy survey of five breeds. J Am Anim Hosp Assoc. 2001;37(5):438–43.
Dobson JM. Breed-predispositions to cancer in pedigree dogs. ISRN Vet Sci. 2013;2013(Article ID 941275):1–23.
Misdorp W, Hart AAM. Some prognostic and epidemiologic factors in canine osteosarcoma. J Natl Cancer Inst. 1979;62(3):537–45.
Cooley DM, Beranek BC, Schlittler DL, Glickman NW, Glickman LT, Waters DJ. Endogenous gonadal hormone exposure and bone sarcoma risk. Cancer Epidemiol Biomark Prev. 2002;11(11):1434.
McNeill CJ, Overley B, Shofer FS, Kent MS, Clifford CA, Samluk M, et al. Characterization of the biological behaviour of appendicular osteosarcoma in Rottweilers and a comparison with other breeds: a review of 258 dogs*. Vet Comp Oncol. 2007;5(2):90–8.
Morello E, Martano M, Buracco P. Biology, diagnosis and treatment of canine appendicular osteosarcoma: similarities and differences with human osteosarcoma. Vet J. 2011;189(3):268–77.
Adams VJ, Evans KM, Sampson J, Wood JLN. Methods and mortality results of a health survey of purebred dogs in the UK. J Small Anim Pract. 2010;51(10):512–24.
Galis F, Van Der Sluijs I, Van Dooren TJM, Metz JAJ, Nussbaumer M. Do large dogs die young? J Exp Zool B Mol Dev Evol. 2007;308B(2):119–26.
Greer KA, Canterberry SC, Murphy KE. Statistical analysis regarding the effects of height and weight on life span of the domestic dog. Res Vet Sci. 2007;82(2):208–14.
Patronek GJ, Waters DJ, Glickman LT. Comparative longevity of pet dogs and humans: implications for gerontology research. J Gerontol Biol Sci. 1997;52(3):B171–B8.
Michell AR. Longevity of British breeds of dog and its relationships with sex, size, cardiovascular variables and disease. Vet Rec. 1999;145(22):625–9.
Selman C, Nussey Daniel H, Monaghan P. Ageing: It’s a dog’s life. Curr Biol. 2013;23(10):R451–R3.
O’Neill DG, Coulson NR, Church DB, Brodbelt DC. Demography and disorders of German shepherd dogs under primary veterinary care in the UK. Canine Genet Epidemiol. 2017;4(1):7.
Svartberg K. Breed-typical behaviour in dogs—historical remnants or recent constructs? Appl Anim Behav Sci. 2006;96(3):293–313.
Rosado B, García-Belenguer S, León M, Palacio J. Spanish dangerous animals act: effect on the epidemiology of dog bites. J Vet Behav Clin App Res. 2007;2(5):166–74.
Takeuchi Y, Mori Y. A comparison of the behavioral profiles of purebred dogs in Japan to profiles of those in the United States and the United Kingdom. J Vet Med Sci. 2006;68(8):789–96.
Hsu Y, Sun L. Factors associated with aggressive responses in pet dogs. Appl Anim Behav Sci. 2010;123(3–4):108–23.
Bradshaw JW, Goodwin D, Lea AM, Whitehead SL. A survey of the behavioural characteristics of pure-bred dogs in the United Kingdom. Vet Rec. 1996;138(19):465–8.
Notari L, Goodwin D. A survey of behavioural characteristics of pure-bred dogs in Italy. Appl Anim Behav Sci. 2007;103(1–2):118–30.
Bamberger M, Houpt KA. Signalment factors, comorbidity, and trends in behavior diagnoses in dogs: 1,644 cases (1991–2001). J Am Vet Med Assoc. 2006;229(10):1591–601.
van der Borg JAM, Graat EAM, Beerda B. Behavioural testing based breeding policy reduces the prevalence of fear and aggression related behaviour in Rottweilers. Appl Anim Behav Sci. 2017; doi: 10.1016/j.applanim.2017.06.004.
Jagoe A, Serpell J. Owner characteristics and interactions and the prevalence of canine behaviour problems. Appl Anim Behav Sci. 1996;47(1/2):31–42.
Gazzano A, Zilocchi M, Massoni E, Mariti C. Dogs’ features strongly affect people’s feelings and behavior toward them. J Vet Behav Clin App Res. 2013;8(4):213–20.
Wrobel TA, Dye AL. Grieving pet death: normative, gender, and attachment issues. OMEGA J Death Dying. 2003;47(4):385–93.
McCutcheon KA, Fleming SJ. Grief resulting from euthanasia and natural death of companion animals. J Death Dying. 2001/2002;44(2):169–88.
Adams CL, Bonnett BN, Meek AH. Predictors of owner response to companion animal death in 177 clients from 14 practices in Ontario. J Am Vet Med Assoc. 2000;217(9):1303–9.
Yeates JW, Mullan S, Stone M, Main DCJ. Promoting discussions and decisions about dogs’ quality-of-life. J Small Anim Pract. 2011;52(9):459–63.
Borchelt PL. Aggressive behavior of dogs kept as companion animals: classification and influence of sex, reproductive status and breed. Appl Anim Ethol. 1983;10(1):45–61.
Blackshaw JK. An overview of types of aggressive behaviour in dogs and methods of treatment. Appl Anim Behav Sci. 1991;30(3):351–61.
Perez-Guisado J, Munoz-Serrano A. Factors linked to territorial aggression in dogs. J Anim Vet Adv. 2009;8(7):1412–8.
Gershman KA, Sacks JJ, Wright JC. Which dogs bite? A case-control study of risk factors. Pediatrics. 1994;93(6):913.
Cameron DB. Canine dominance-associated aggression: concepts, incidence, and treatment in a private behavior practice. Appl Anim Behav Sci. 1997;52(3/4):265–73.
Podberscek AL, Serpell JA: The English cocker spaniel: preliminary findings on aggressive behaviour. Applied Animal Behaviour Science. 1996,47(1):75-89.
Guy NC, Luescher UA, Dohoo SE, Spangler E, Miller JB, Dohoo IR, et al. Demographic and aggressive characteristics of dogs in a general veterinary caseload. Appl Anim Behav Sci. 2001;74(1):15–28.
Bennett PC, Rohlf VI. Owner-companion dog interactions: relationships between demographic variables, potentially problematic behaviours, training engagement and shared activities. Appl Anim Behav Sci. 2007;102(1):65–84.
Casey RA, Loftus B, Bolster C, Richards GJ, Blackwell EJ. Human directed aggression in domestic dogs (Canis Familiaris): occurrence in different contexts and risk factors. Appl Anim Behav Sci. 2014;152(2014):52–63.
Messam LLM, Kass PH, Chomel BB, Hart LA. The human–canine environment: a risk factor for non-play bites? Vet J. 2008;177(2):205–15.
Spain CV, Scarlett JM, Houpt KA. Long-term risks and benefits of early-age gonadectomy in dogs. J Am Vet Med Assoc. 2004;224(3):380–7.
Holm BR, Rest JR, Seewald W. A prospective study of the clinical findings, treatment and histopathology of 44 cases of pyotraumatic dermatitis. Vet Dermatol. 2004;15(6):369–76.
Scott DW, Miller WH, Griffin CE, Muller GH. Muller & Kirk’s small animal dermatology. 6th ed. Philadelphia: Saunders; 2001.
Schaer M. Clinical medicine of the dog and cat. 2nd ed. London: Manson/Veterinary Press; 2010.
McGreevy PD, Thomson PC, Pride C, Fawcett A, Grassi T, Jones B. Prevalence of obesity in dogs examined by Australian veterinary practices and the risk factors involved. Vet Rec. 2005;156(22):695–702.
Lund EM, Armstrong PJ, Kirk CA, Klausner JS. Prevalence and risk factors for obesity in adult dogs from private US veterinary practices. Int J Appl Res Vet Med. 2006;4(2):177–86.
Colliard L, Ancel J, Benet J-J, Paragon B-M, Blanchard G. Risk factors for obesity in dogs in France. J Nutr. 2006;136(7):1951S–4S.
Mao J, Xia Z, Chen J, Yu J. Prevalence and risk factors for canine obesity surveyed in veterinary practices in Beijing, China. Prev Vet Med. 2013;112(3–4):438–42.
Robinson NJ, Dean RS, Cobb M, Brennan ML. Factors influencing common diagnoses made during first-opinion small-animal consultations in the United Kingdom. Prev Vet Med. 2016;131:87–94.
German AJ. The growing problem of obesity in dogs and cats. J Nutr. 2006;136(7):1940S–6S.
German AJ. Weight management in obese pets: the tailoring concept and how it can improve results. Acta Vet Scand. 2016;58(1):57.
Marsella R, Girolomoni G. Canine models of atopic dermatitis: a useful tool with untapped potential. J Invest Dermatol. 2009;129(10):2351–7.
Paterson S. Discovering the causes of otitis externa. In Pract. 2016;38(Suppl 2):7–11.
Pettitt RA, German AJ. Investigation and management of canine osteoarthritis. In Pract. 2015;37(Suppl 1):1–8.