Canine Medicine and Genetics

Table 2 Haplotype frequencies (%) observed in the six highest risk breeds included in the study

From: Dog leucocyte antigen (DLA) class II haplotypes and risk of canine diabetes mellitus in specific dog breeds

Haplotype ID	Haplotype			Samoyed		Tibetan Terrier		Cairn Terrier		Miniature Schnauzer		WHWT		Border Collie
Haplotype ID	DRB1	DQA1	DQB1	Cases n = 43	Cntr n = 70	Cases n = 20	Cntr n = 40	Cases n = 30	Cntr n = 30	Cases n = 28	Cntr n = 38	Cases n = 133	Cntr n = 150	Cases n = 57	Cntr n = 87
1	001:01	001:01	002:01			2.5	5.0	5.0	10.0		3.9	39.5	39.7	6.1	3.4
2	001:01	001:01	036:01			17.5	11.3			21.4	14.5	0	2.0	2.6	2.9
3	001:01	009:01	001:01									21.8	25.0
4	002:01	009:01	001:01						3.3					16.7	4.9
9	009:01	001:01	008:01:1							58.9	64.5			4.4
10	009:01	001:01	008:02	23.5	17.1									3.5	4.0
15	013:01	001:01	002:01							8.9	6.6			12.3	21.8
16	015:01	006:01	003:01		3.6				8.3
17	015:01	006:01	011:01					3.3				7.1	7.7
18	015:01	006:01	019:01–054:02	63.2	65.0
19	015:01	006:01	020:02						3.3			17.7	14.3
21	015:01	006:01	023:01			15.0	11.3	43.3	35.0			6.8	4.3	24.6	17.8
22	015:01	006:01	026:01			7.5	18.8
23	015:01	009:01	001:01									4.1	3.7
24	015:02	006:01	003:01								2.6
25	015:02	006:01	023:01			17.5	15.0	35.0	21.7	3.6	6.6			3.5	4.6
26	018:01	001:01	002:01											7.9	9.6
28	020:01	004:01	013:03	7.4	10.0
29	023:01	003:01	005:01							3.6				7.9	6.9
30	079:01	001:01	002:01			30.0	26.3
	001:01	002:01	036:01			2.5
	003:01	001:01	008:01:1			2.5	5.0	10.0	13.3
	015:02	006:01	054:01			2.5
	040:01	010:01	019:01	4.4	3.6
	112:01	001:01	008:01:2			2.5	3.8

Only haplotypes with a frequency > 2% are shown. Haplotypes which were significantly different between cases and controls in an individual breed are shown in bold. Haplotypes are sorted by haplotype ID, where these were assigned (Supplementary Table 2; assigned to the 30 most commonly observed haplotypes for ease of reference throughout the study). Breeds are listed in order of breed risk for DM, as indicated in Table 1. n = number of dogs, Cntr Controls, WHWT West highland White Terrier

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