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Table 4 Breed-specific analysis (only significant haplotypes and breeds shown)

From: Dog leucocyte antigen (DLA) class II haplotypes and risk of canine diabetes mellitus in specific dog breeds

Breed
(n cases/n controls)
Haplotype ID Haplotype Cases
%
Controls
%
Odds ratio 95% Confidence interval Protective/Risk Number of other breeds carrying haplotype
DRB1 DQA1 DQB1
Border Terrier
(27/27)
19 015:01 006:01 020:02 7.4 27.8 0.211 0.05–0.73 Protective 6
CKCS
(48/48)
28 020:01 004:01 013:03 35.4 16.7 2.73 1.33–5.81 Risk 5
Cocker Spaniel
(55/80)
6 006:01 005:01:1 007:01 89.1 56.3 6.31 3.14–13.65 Risk 6
7 006:01 005:01:1 020:01 8.2 23.1 0.297 0.12–0.66 Protective 3
14 012:01 004:01 017:01–013:03 0.0 5.0 N/A 0–0.83 Protective 4
19 015:01 006:01 020:02 0.0 6.9 N/A 0–0.56 Protective 6
Labrador Retriever
(111/240)
1 001:01 001:01 002:01 20.3 13.8 1.59 1.02–2.47 Risk 7
WHWT
(133/150)
2 001:01 001:01 036:01 0.0 2.0 N/A 0–0.95 Protective 7
  1. DLA class II haplotypes significantly associated (upper and lower 95% confidence intervals did not cross 1) with diabetes mellitus in individual breeds, calculated using Fisher’s exact test. n = number of dogs, CKCS Cavalier King Charles Spaniel, WHWT West highland White Terrier, N/A Not applicable