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Table 4 CTLA4 promoter haplotypes present in springer spaniels. Number of each haplotype is shown (with frequency in brackets) for cases, 2n = 56, and controls, 2n = 114. NaN: not a number; OR: odds ratio; 95% CI: 95% confidence intervals of the OR. p values for individual 2 × 2 tables are given with significant results coloured red, overall significance p = 0.291

From: Polymorphisms in the CTLA4 promoter sequence are associated with canine hypoadrenocorticism

CTLA4 promoter HaplotypeCases
2n (%)
Controls
2n (%)
pOR
95% CI
227 (48.2%)34 (29.8%)0.02662.19 (1.13–4.23)
31 (1.78%)2 (1.75%)11.01 (0.09–11.4)
821 (37.5%)57 (50%)0.14230.6 (0.31–1.15)
100 (0%)1 (0.87%)10
110 (0%)3 (2.63%)0.55160
127 (12.5%)16 (14.0%)10.87 (0.33–2.26)
150 (0%)1 (0.87%)10