Table 4 CTLA4 promoter haplotypes present in springer spaniels. Number of each haplotype is shown (with frequency in brackets) for cases, 2n = 56, and controls, 2n = 114. NaN: not a number; OR: odds ratio; 95% CI: 95% confidence intervals of the OR. p values for individual 2 × 2 tables are given with significant results coloured red, overall significance p = 0.291
From: Polymorphisms in the CTLA4 promoter sequence are associated with canine hypoadrenocorticism
CTLA4 promoter Haplotype | Cases 2n (%) | Controls 2n (%) | p | OR 95% CI |
|---|---|---|---|---|
2 | 27 (48.2%) | 34 (29.8%) | 0.0266 | 2.19 (1.13–4.23) |
3 | 1 (1.78%) | 2 (1.75%) | 1 | 1.01 (0.09–11.4) |
8 | 21 (37.5%) | 57 (50%) | 0.1423 | 0.6 (0.31–1.15) |
10 | 0 (0%) | 1 (0.87%) | 1 | 0 |
11 | 0 (0%) | 3 (2.63%) | 0.5516 | 0 |
12 | 7 (12.5%) | 16 (14.0%) | 1 | 0.87 (0.33–2.26) |
15 | 0 (0%) | 1 (0.87%) | 1 | 0 |