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Page 1 of 2
Atrial fibrillation (AF) is the most common arrhythmia in dogs. The Irish Wolfhound breed has a high prevalence of AF making them an ideal breed to investigate possible genetic contributions to this disease. T...
Citation: Canine Genetics and Epidemiology 2019 6:11
Making assumptions regarding temperament and intelligence based on the physical appearance of dogs can be a conscious or unconscious human act. Labrador retrievers with chocolate-coloured coats are anecdotally...
Citation: Canine Genetics and Epidemiology 2019 6:10
N-glycolylneuraminic acid (Neu5Gc) is synthesized from its precursor N-acetylneuraminic acid (Neu5Ac) by cytidine-5′-monophospho-N acetylneuraminic acid hydroxylase (CMAH), which is encoded by the CMAH gene. Most...
Citation: Canine Genetics and Epidemiology 2019 6:9
In the original publication of this article [1], due to an error in a single count relating to the denominator used for this study, some of the derived values were wrong, so that abstract, plain English summar...
Citation: Canine Genetics and Epidemiology 2019 6:8
The West Highland White Terrier (WHWT) is a relatively common breed in the UK, although Kennel Club registrations have declined in recent years. The VetCompass™ Programme collates de-identified clinical data f...
Citation: Canine Genetics and Epidemiology 2019 6:7
The absence of selective pressure against recessive deleterious mutations in the heterozygous state means that virtually every individual will carry several such mutations which have arisen over time. The infl...
Citation: Canine Genetics and Epidemiology 2019 6:6
The greyhound is a sighthound known for its speed and agility. Greyhounds were selectively bred as functional racing animals but increasingly are kept as pets in the UK, often after their racing careers are ov...
Citation: Canine Genetics and Epidemiology 2019 6:4
In humans, ADAMTS17 mutations are known to cause Weill-Marchesani-like syndrome, which is characterised by lenticular myopia, ectopia lentis, glaucoma, spherophakia, and short stature. Breed-specific homozygous m...
Citation: Canine Genetics and Epidemiology 2019 6:5
Von Willebrand disorder type I (vWDI) is known as an inherited bleeding disorder in different dog breeds following an autosomal recessive inheritance. The Kromfohrländer is a rare dog breed with an increased i...
Citation: Canine Genetics and Epidemiology 2019 6:3
Primary hypoadrenocorticism (Addison’s disease, AD) and symmetrical lupoid onychodystrophy (SLO) are two clinical conditions with an autoimmune etiology that occur in multiple dog breeds. In man, autoimmunity ...
Citation: Canine Genetics and Epidemiology 2019 6:2
Individual dog breeds are often reported as predisposed to specific breed-related disorders but reliable epidemiological data on disease prevalence are sparse. The Miniature Schnauzer in the UK is a popular sm...
Citation: Canine Genetics and Epidemiology 2019 6:1
Selective breeding in populations with a limited effective population size may result in a loss of genetic diversity, which can cause an increased concentration of specific disease liability genes. The Dutch S...
Citation: Canine Genetics and Epidemiology 2018 5:12
Intervertebral disc herniation (IVDH) involves displacement of the intervertebral disc secondary to disc degeneration and is extremely common in dachshunds. Clinical signs include pain with or without paresis ...
Citation: Canine Genetics and Epidemiology 2018 5:11
Labrador retrievers are reportedly predisposed to many disorders but accurate prevalence information relating to the general population are lacking. This study aimed to describe demography, mortality and commo...
Citation: Canine Genetics and Epidemiology 2018 5:8
The domestic dog is one of the most diverse mammalian species, exhibiting wide variations in morphology, behaviour and morbidity across breeds. Therefore, it is not unexpected that breeds should also exhibit v...
Citation: Canine Genetics and Epidemiology 2018 5:10
Lipomas are masses of mesenchymal origin, comprising of adipocytes, and are often clinically unremarkable but can be alarming to owners. Although lipomas are reportedly common in dogs, no studies have specific...
Citation: Canine Genetics and Epidemiology 2018 5:9
Citation: Canine Genetics and Epidemiology 2018 5(Suppl 2):7
Citation: Canine Genetics and Epidemiology 2018 5(Suppl 1):6
Working dog handlers and breeders have very different behavioural requirements in the animals that they employ for managing livestock. The Australian Working Kelpie breed may be used in several working context...
Citation: Canine Genetics and Epidemiology 2018 5:5
Despite its Gallic name, the French Bulldog is a breed of both British and French origin that was first recognised by The Kennel Club in 1906. The French Bulldog has demonstrated recent rapid rises in Kennel C...
Citation: Canine Genetics and Epidemiology 2018 5:3
Citation: Canine Genetics and Epidemiology 2018 5:4
Canine DNA-testing has become an important tool in purebred dog breeding and many breeders use genetic testing results when planning their breeding strategies. In addition, information obtained from testing of...
Citation: Canine Genetics and Epidemiology 2018 5:2
The selection of a future breeding dog is a complicated task, in which disease characteristics and different traits have to be combined and weighed against one another. Truncation selection, that is the exclus...
Citation: Canine Genetics and Epidemiology 2018 5:1
Breed-related health problems in dogs have received increased focus over the last decade. Responsibility for causing and/or solving these problems has been variously directed towards dog breeders and kennel cl...
Citation: Canine Genetics and Epidemiology 2017 4:16
The Border Terrier is a working terrier type that is generally considered to be a relatively healthy and hardy breed. This study aimed to characterise the demography and common disorders of Border Terriers rec...
Citation: Canine Genetics and Epidemiology 2017 4:15
Rottweilers are reportedly predisposed to many disorders but accurate prevalence information relating to the general population are lacking. This study aimed to describe demography, mortality and commonly reco...
Citation: Canine Genetics and Epidemiology 2017 4:13
Pure breeding of dogs has led to over 700 heritable disorders, of which almost 300 are Mendelian in nature. Seventy percent of the characterized mutations have an autosomal recessive mode of inheritance, indic...
Citation: Canine Genetics and Epidemiology 2017 4:11
Studying cancer and other diseases poses a problem due to their protracted and multifactorial nature. Prospective studies are useful to investigate chronic disease processes since collection of lifestyle infor...
Citation: Canine Genetics and Epidemiology 2017 4:14
Canine lumbosacral stenosis is defined as narrowing of the caudal lumbar and/or sacral vertebral canal. A risk factor for neurologic problems in many large sized breeds, lumbosacral stenosis can also cause ear...
Citation: Canine Genetics and Epidemiology 2017 4:12
Genetic polymorphisms within the glutathione S-transferase P1 (GSTP1) gene affect the elimination of toxic xenobiotics by the GSTP1 enzyme. In dogs, exposure to environmental chemicals that may be GSTP1 substrate...
Citation: Canine Genetics and Epidemiology 2017 4:9
Citation: Canine Genetics and Epidemiology 2017 4:10
Pedigree or purebred dogs are often stated to have high prevalence of disorders which are commonly assumed to be a consequence of inbreeding and selection for exaggerated features. However, few studies empiric...
Citation: Canine Genetics and Epidemiology 2017 4:8
The German Shepherd Dog (GSD) has been widely used for a variety of working roles. However, concerns for the health and welfare of the GSD have been widely aired and there is evidence that breed numbers are no...
Citation: Canine Genetics and Epidemiology 2017 4:7
Corneal ulcerative disease (CUD) has the potential to adversely affect animal welfare by interfering with vision and causing pain. The study aimed to investigate for the first time the prevalence, breed-based ...
Citation: Canine Genetics and Epidemiology 2017 4:5
Gonadectomy, or neutering, is a very common surgery for dogs having many positive effects on behavior, health, and longevity. There are also certain risks associated with neutering including the development of...
Citation: Canine Genetics and Epidemiology 2017 4:6
Concentrated breeding effort to produce various body structures and behaviors of dogs to suit human demand has inadvertently produced unwanted traits and diseases that accompany the morphological and behaviora...
Citation: Canine Genetics and Epidemiology 2017 4:4
Osteosarcoma is the most common neoplastic disease in Scottish Deerhounds. For Deerhounds, a 2007 population-based study concluded that a single dominant genetic factor largely governed disease risk. For Greyh...
Citation: Canine Genetics and Epidemiology 2017 4:3
Exercise-induced collapse (EIC) due to DNM1 mutation and rupture of the cranial cruciate ligament are both common syndromes in the Labrador retriever breed. A cohort of 313 Labradors was recruited based on their ...
Citation: Canine Genetics and Epidemiology 2017 4:2
In humans, reduced activity of the enzyme monoamine oxidase type A (MAOA) due to genetic polymorphisms within the MAOA gene leads to increased brain neurotransmitter levels associated with aggression. In order to...
Citation: Canine Genetics and Epidemiology 2017 4:1
Despite decades of studying, the mechanisms maintaining high diversity in the genes of the Major Histocompatibility Complex (MHC) are still puzzling scientists. In addition to pathogen recognition and other fu...
Citation: Canine Genetics and Epidemiology 2016 3:9
Intervertebral disc disease (IVDD) represents a major problem in the Dachshund, with at a relative risk of IVDD 10–12 times higher than other breeds, and an estimated 19–24 % of Dachshunds showing clinical sig...
Citation: Canine Genetics and Epidemiology 2016 3:8
This study examines genetic diversity among 102 registered English Bulldogs used for breeding based on maternal and paternal haplotypes, allele frequencies in 33 highly polymorphic short tandem repeat (STR) lo...
Citation: Canine Genetics and Epidemiology 2016 3:6
Progressive retinal atrophy (PRA) belongs to a group of inherited retinal disorders associated with gradual vision impairment due to degeneration of retinal photoreceptors in various dog breeds. PRA is highly ...
Citation: Canine Genetics and Epidemiology 2016 3:7
The Pug is an ancient dog breed and was the fifth most commonly registered UK pedigree breed in 2014. However, the breed has been reported to be predisposed to several disorders including ocular, respiratory a...
Citation: Canine Genetics and Epidemiology 2016 3:5
Canine patellar luxation is one of the most common orthopaedic disorders of dogs and is a potential welfare concern because it can lead to lameness, osteoarthritis and pain. However, there are limited epidemio...
Citation: Canine Genetics and Epidemiology 2016 3:4
Valued for trainability in diverse tasks, dogs are the primary service animal used to assist individuals with disabilities. Despite their utility, many people in need of service dogs are sensitive to the prima...
Citation: Canine Genetics and Epidemiology 2016 3:3
The morphology of dogs can provide information about their predisposition to some disorders. For example, larger breeds are predisposed to hip dysplasia and many neoplastic diseases. Therefore, longitudinal tr...
Citation: Canine Genetics and Epidemiology 2016 3:2
The aims of this study were to: determine the prevalence of pectinate ligament dysplasia (PLD) in populations of Basset hounds (BH), Flatcoated retrievers (FCR) and Dandie Dinmont terriers (DDT) resident in th...
Citation: Canine Genetics and Epidemiology 2016 3:1
Previous studies documented the problem of inbreeding among Italian Greyhounds (IG) from the USA and its possible role in a multiple autoimmune disease syndrome. The present study is an extension of these earl...
Citation: Canine Genetics and Epidemiology 2015 2:17
Next generation sequencing (NGS) has traditionally been performed by large genome centers, but in recent years, the costs for whole-genome sequencing (WGS) have decreased substantially. With the introduction o...
Citation: Canine Genetics and Epidemiology 2015 2:16
Speed
44 days to first decision for reviewed manuscripts only
44 days to first decision for all manuscripts
88 days from submission to acceptance
30 days from acceptance to publication
Usage
123,214 downloads
237 Altmetric mentions
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