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29 days to first decision for reviewed manuscripts only
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Page 2 of 2
Pedigree or purebred dogs are often stated to have high prevalence of disorders which are commonly assumed to be a consequence of inbreeding and selection for exaggerated features. However, few studies empiric...
Citation: Canine Genetics and Epidemiology 2017 4:8
The German Shepherd Dog (GSD) has been widely used for a variety of working roles. However, concerns for the health and welfare of the GSD have been widely aired and there is evidence that breed numbers are no...
Citation: Canine Genetics and Epidemiology 2017 4:7
Corneal ulcerative disease (CUD) has the potential to adversely affect animal welfare by interfering with vision and causing pain. The study aimed to investigate for the first time the prevalence, breed-based ...
Citation: Canine Genetics and Epidemiology 2017 4:5
Gonadectomy, or neutering, is a very common surgery for dogs having many positive effects on behavior, health, and longevity. There are also certain risks associated with neutering including the development of...
Citation: Canine Genetics and Epidemiology 2017 4:6
Concentrated breeding effort to produce various body structures and behaviors of dogs to suit human demand has inadvertently produced unwanted traits and diseases that accompany the morphological and behaviora...
Citation: Canine Genetics and Epidemiology 2017 4:4
Osteosarcoma is the most common neoplastic disease in Scottish Deerhounds. For Deerhounds, a 2007 population-based study concluded that a single dominant genetic factor largely governed disease risk. For Greyh...
Citation: Canine Genetics and Epidemiology 2017 4:3
Exercise-induced collapse (EIC) due to DNM1 mutation and rupture of the cranial cruciate ligament are both common syndromes in the Labrador retriever breed. A cohort of 313 Labradors was recruited based on their ...
Citation: Canine Genetics and Epidemiology 2017 4:2
In humans, reduced activity of the enzyme monoamine oxidase type A (MAOA) due to genetic polymorphisms within the MAOA gene leads to increased brain neurotransmitter levels associated with aggression. In order to...
Citation: Canine Genetics and Epidemiology 2017 4:1
Despite decades of studying, the mechanisms maintaining high diversity in the genes of the Major Histocompatibility Complex (MHC) are still puzzling scientists. In addition to pathogen recognition and other fu...
Citation: Canine Genetics and Epidemiology 2016 3:9
Intervertebral disc disease (IVDD) represents a major problem in the Dachshund, with at a relative risk of IVDD 10–12 times higher than other breeds, and an estimated 19–24 % of Dachshunds showing clinical sig...
Citation: Canine Genetics and Epidemiology 2016 3:8
This study examines genetic diversity among 102 registered English Bulldogs used for breeding based on maternal and paternal haplotypes, allele frequencies in 33 highly polymorphic short tandem repeat (STR) lo...
Citation: Canine Genetics and Epidemiology 2016 3:6
Progressive retinal atrophy (PRA) belongs to a group of inherited retinal disorders associated with gradual vision impairment due to degeneration of retinal photoreceptors in various dog breeds. PRA is highly ...
Citation: Canine Genetics and Epidemiology 2016 3:7
The Pug is an ancient dog breed and was the fifth most commonly registered UK pedigree breed in 2014. However, the breed has been reported to be predisposed to several disorders including ocular, respiratory a...
Citation: Canine Genetics and Epidemiology 2016 3:5
Canine patellar luxation is one of the most common orthopaedic disorders of dogs and is a potential welfare concern because it can lead to lameness, osteoarthritis and pain. However, there are limited epidemio...
Citation: Canine Genetics and Epidemiology 2016 3:4
Valued for trainability in diverse tasks, dogs are the primary service animal used to assist individuals with disabilities. Despite their utility, many people in need of service dogs are sensitive to the prima...
Citation: Canine Genetics and Epidemiology 2016 3:3
The morphology of dogs can provide information about their predisposition to some disorders. For example, larger breeds are predisposed to hip dysplasia and many neoplastic diseases. Therefore, longitudinal tr...
Citation: Canine Genetics and Epidemiology 2016 3:2
The aims of this study were to: determine the prevalence of pectinate ligament dysplasia (PLD) in populations of Basset hounds (BH), Flatcoated retrievers (FCR) and Dandie Dinmont terriers (DDT) resident in th...
Citation: Canine Genetics and Epidemiology 2016 3:1
Previous studies documented the problem of inbreeding among Italian Greyhounds (IG) from the USA and its possible role in a multiple autoimmune disease syndrome. The present study is an extension of these earl...
Citation: Canine Genetics and Epidemiology 2015 2:17
Next generation sequencing (NGS) has traditionally been performed by large genome centers, but in recent years, the costs for whole-genome sequencing (WGS) have decreased substantially. With the introduction o...
Citation: Canine Genetics and Epidemiology 2015 2:16
Inbreeding is inevitable in closed populations with a finite number of ancestors and where there is selection. Therefore, management of the rate of inbreeding at sustainable levels is required to avoid the ass...
Citation: Canine Genetics and Epidemiology 2015 2:13
Urothelial carcinoma (UC), also known as transitional cell carcinoma (TCC), of the bladder is the most common neoplasm affecting the canine urogenital system. To facilitate study of the disease in vitro, cell lin...
Citation: Canine Genetics and Epidemiology 2015 2:15
Sebaceous adenitis (SA) and Addison’s disease (AD) increased rapidly in incidence among Standard Poodles after the mid-twentieth century. Previous attempts to identify specific genetic causes using genome wide...
Citation: Canine Genetics and Epidemiology 2015 2:14
Hypothyroidism is one of the most common endocrine disorders, whereas symmetrical onychomadesis is a rare claw disease in the general dog population. The aims of this study were to estimate the prevalence of h...
Citation: Canine Genetics and Epidemiology 2015 2:12
Canine distichiasis is a well-known cause of ocular irritation and excessive lacrimation (secretion of tears) in the dog. The term distichiasis originates from the Greek words di and stichos meaning two and rows,...
Citation: Canine Genetics and Epidemiology 2015 2:11
Brachycephalic dog breeds are increasingly common. Canine brachycephaly has been associated with upper respiratory tract (URT) disorders but reliable prevalence data remain lacking. Using primary-care veterina...
Citation: Canine Genetics and Epidemiology 2015 2:10
Analysis of 88,635 dogs seen at the University of California, Davis Veterinary Medical Teaching Hospital from 1995 to 2010 identified ten inherited conditions having greater prevalence within the purebred dog ...
Citation: Canine Genetics and Epidemiology 2015 2:9
Cocker spaniels are predisposed to immune-mediated haemolytic anaemia (IMHA), suggesting that genetic factors influence disease susceptibility. Dog leukocyte antigen (DLA) class II genes encode major histocomp...
Citation: Canine Genetics and Epidemiology 2015 2:8
A Norfolk terrier was referred to the Animal Health Trust neurology department with suspected dystrophin-deficient muscular dystrophy (DD-MD), which was confirmed by clinical workup and immunohistochemistry.
Citation: Canine Genetics and Epidemiology 2015 2:7
Working dog handlers and breeders have strong opinions on characteristics that are desirable in the breeds that they use to handle stock. Most of these characteristics are related to conformation or behaviour....
Citation: Canine Genetics and Epidemiology 2015 2:6
The domestic dog represents an important model for studying the genetics of behavior. In spite of technological advances in genomics and phenomics, the genetic basis of most specific canine behaviors is largel...
Citation: Canine Genetics and Epidemiology 2015 2:5
Concerns have been raised over breed-related health issues in purebred dogs, but reliable prevalence estimates for disorders within specific breeds are sparse. Electronically stored patient health records from...
Citation: Canine Genetics and Epidemiology 2015 2:4
The issue of inherited disorders and poor health in pedigree dogs has been widely discussed in recent years. With the advent of genome-wide sequencing technologies and the increasing development of new diagnos...
Citation: Canine Genetics and Epidemiology 2015 2:3
The breed-defining dorsal ridge in Rhodesian Ridgeback dogs is the result of a 133,000 base pair duplication on chromosome 18. Because this trait is dominant, heterozygous dogs cannot be discriminated from tho...
Citation: Canine Genetics and Epidemiology 2015 2:2
Mast cell tumour (MCT) appears to be a frequent tumour type in dogs, though there is little published in relation to its frequency in dogs in the UK. The current study aimed to investigate prevalence and risk ...
Citation: Canine Genetics and Epidemiology 2015 2:1
Toll-like receptors (TLRs) are pattern recognition receptors (PRRs) considered to be the primary sensors of pathogens in innate immunity. Genetic variants could be associated to differences in breed innate imm...
Citation: Canine Genetics and Epidemiology 2014 1:11
Canine degenerative myelopathy (CDM) is an adult onset, progressive neurodegenerative disease of the spinal cord. The disease was originally described in the German Shepherd dog (GSD), but it is now known to o...
Citation: Canine Genetics and Epidemiology 2014 1:10
Syringomyelia (SM) is a painful neurological condition, prevalent in brachycephalic toy breeds including the Cavalier King Charles Spaniel (CKCS). In these breeds, SM is typically secondary to Chiari-like Malf...
Citation: Canine Genetics and Epidemiology 2014 1:9
Canine diabetes is a common endocrine disorder with an estimated breed-related prevalence ranging from 0.005% to 1.5% in pet dogs. Increased prevalence in some breeds suggests that diabetes in dogs is influenc...
Citation: Canine Genetics and Epidemiology 2014 1:8
Canine behaviours that are both desirable and undesirable to owners have a demonstrable genetic component. Some behaviours are breed-specific, such as the livestock guarding by maremmas and flank sucking seen ...
Citation: Canine Genetics and Epidemiology 2014 1:7
During routine diagnostic BAER testing of dogs of various breeds for private owners at the Western College of Veterinary Medicine in Saskatoon, it became evident that some individual dogs developed hearing los...
Citation: Canine Genetics and Epidemiology 2014 1:6
This paper addresses the use of cohort studies in canine medicine to date and highlights the benefits of wider use of such studies in the future. Uniquely amongst observational studies, cohort studies offer th...
Citation: Canine Genetics and Epidemiology 2014 1:5
Generalized progressive retinal atrophy (PRA) is a group of inherited eye diseases characterised by progressive retinal degeneration that ultimately leads to blindness in dogs. To date, more than 20 different ...
Citation: Canine Genetics and Epidemiology 2014 1:4
Inherited forms of eye disease are arguably the best described and best characterized of all inherited diseases in the dog, at both the clinical and molecular level and at the time of writing 29 different muta...
Citation: Canine Genetics and Epidemiology 2014 1:3
Effective canine health surveillance systems can be used to monitor disease in the general population, prioritise disorders for strategic control and focus clinical research, and to evaluate the success of the...
Citation: Canine Genetics and Epidemiology 2014 1:2
Citation: Canine Genetics and Epidemiology 2014 1:1
Speed
29 days to first decision for reviewed manuscripts only
29 days to first decision for all manuscripts
67 days from submission to acceptance
23 days from acceptance to publication
Usage
115,793 downloads
84 Altmetric mentions
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